HCSGD entry for KCND3
1. General information
| Official gene symbol | KCND3 |
|---|---|
| Entrez ID | 3752 |
| Gene full name | potassium voltage-gated channel, Shal-related subfamily, member 3 |
| Other gene symbols | KCND3L KCND3S KSHIVB KV4.3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005250 | A-type (transient outward) potassium channel activity | IBA IDA | molecular_function |
| GO:0005251 | Delayed rectifier potassium channel activity | IBA | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0006813 | Potassium ion transport | TAS | biological_process |
| GO:0007268 | Synaptic transmission | TAS | biological_process |
| GO:0008076 | Voltage-gated potassium channel complex | IDA | cellular_component |
| GO:0030425 | Dendrite | IEA | cellular_component |
| GO:0042383 | Sarcolemma | IEA | cellular_component |
| GO:0043025 | Neuronal cell body | IEA | cellular_component |
| GO:0044325 | Ion channel binding | IPI | molecular_function |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0051260 | Protein homooligomerization | IEA | biological_process |
| GO:0071435 | Potassium ion export | IDA | biological_process |
| GO:0086009 | Membrane repolarization | IDA | biological_process |
| GO:0097038 | Perinuclear endoplasmic reticulum | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3074408115 | 0.5356826146 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1212342966 |
| GSE13712_SHEAR | Down | -0.1308602209 |
| GSE13712_STATIC | Down | -0.1935405323 |
| GSE19018 | Up | 0.0284380243 |
| GSE19899_A1 | Down | -0.0471117737 |
| GSE19899_A2 | Up | 0.1610089931 |
| PubMed_21979375_A1 | Down | -0.0177386622 |
| PubMed_21979375_A2 | Down | -0.0755900494 |
| GSE35957 | Up | 0.2300302953 |
| GSE36640 | Up | 0.1139856928 |
| GSE54402 | Up | 0.1140788576 |
| GSE9593 | Up | 0.0573333457 |
| GSE43922 | Up | 0.0024144182 |
| GSE24585 | Down | -0.2512219785 |
| GSE37065 | Down | -0.3690785736 |
| GSE28863_A1 | Up | 0.6666436305 |
| GSE28863_A2 | Down | -0.0579050874 |
| GSE28863_A3 | Up | 0.8738085436 |
| GSE28863_A4 | Up | 0.0452746846 |
| GSE48662 | Up | 0.0780650829 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-142-3p | MIMAT0000434 | MIRT021549 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-449c-5p | MIMAT0010251 | MIRT035756 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT051143 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
