HCSGD entry for KCNC4
1. General information
| Official gene symbol | KCNC4 |
|---|---|
| Entrez ID | 3749 |
| Gene full name | potassium voltage-gated channel, Shaw-related subfamily, member 4 |
| Other gene symbols | C1orf30 HKSHIIIC KSHIIIC KV3.4 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005249 | Voltage-gated potassium channel activity | IEA TAS | molecular_function |
| GO:0005251 | Delayed rectifier potassium channel activity | IBA | molecular_function |
| GO:0005267 | Potassium channel activity | TAS | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0006813 | Potassium ion transport | TAS | biological_process |
| GO:0007268 | Synaptic transmission | TAS | biological_process |
| GO:0008076 | Voltage-gated potassium channel complex | IEA | cellular_component |
| GO:0031594 | Neuromuscular junction | IEA | cellular_component |
| GO:0043679 | Axon terminus | IEA | cellular_component |
| GO:0046928 | Regulation of neurotransmitter secretion | IEA | biological_process |
| GO:0051260 | Protein homooligomerization | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0222909768 | 0.9693109646 | 0.3572658551 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.5553953709 |
| GSE13712_SHEAR | Up | 0.9575391492 |
| GSE13712_STATIC | Down | -0.1051865517 |
| GSE19018 | Up | 0.1568955246 |
| GSE19899_A1 | Up | 0.1739787056 |
| GSE19899_A2 | Up | 0.8590809637 |
| PubMed_21979375_A1 | Up | 0.7424092075 |
| PubMed_21979375_A2 | Up | 0.7503008378 |
| GSE35957 | Up | 0.1891485791 |
| GSE36640 | Up | 0.0434684229 |
| GSE54402 | Up | 0.5196962515 |
| GSE9593 | Up | 0.1785959893 |
| GSE43922 | Up | 0.2618033138 |
| GSE24585 | Down | -0.4009685658 |
| GSE37065 | Up | 0.0440199297 |
| GSE28863_A1 | Down | -0.1769360394 |
| GSE28863_A2 | Up | 0.2295573300 |
| GSE28863_A3 | Down | -0.1241504618 |
| GSE28863_A4 | Down | -0.0360453454 |
| GSE48662 | Up | 0.1649564612 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Phosphonoserine | DB04522 | EXPT02883 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022478 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-103a-3p | MIMAT0000101 | MIRT027123 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031651 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031651 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052053 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
