HCSGD entry for KCNC3

1. General information

Official gene symbolKCNC3
Entrez ID3748
Gene full namepotassium voltage-gated channel, Shaw-related subfamily, member 3
Other gene symbolsKSHIIID KV3.3 SCA13
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005249Voltage-gated potassium channel activityIEA TASmolecular_function
GO:0005251Delayed rectifier potassium channel activityIBAmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0006813Potassium ion transportTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0008076Voltage-gated potassium channel complexIEAcellular_component
GO:0008219Cell deathIEAbiological_process
GO:0030673AxolemmaIEAcellular_component
GO:0031594Neuromuscular junctionIEAcellular_component
GO:0032590Dendrite membraneIEAcellular_component
GO:0032809Neuronal cell body membraneIEAcellular_component
GO:0043679Axon terminusIEAcellular_component
GO:0046928Regulation of neurotransmitter secretionIEAbiological_process
GO:0051260Protein homooligomerizationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.22465509290.93189428590.90525822111.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0874024327
GSE13712_SHEARDown-0.1358011769
GSE13712_STATICDown-0.0277979185
GSE19018Up0.1493814393
GSE19899_A1Up0.0105035787
GSE19899_A2Up0.0570806979
PubMed_21979375_A1Up0.1010759613
PubMed_21979375_A2Up0.0689048252
GSE35957Up0.1495567457
GSE36640Up0.2308638102
GSE54402Up0.4938013790
GSE9593Down-0.0008085683
GSE43922Up0.0608567796
GSE24585Down-0.0060692528
GSE37065Up0.1118166632
GSE28863_A1Down-0.2358516763
GSE28863_A2Down-0.0609916869
GSE28863_A3Up0.5848028004
GSE28863_A4Up0.0511014622
GSE48662Up0.2623320587

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

DalfampridineDB06637 -

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.