HCSGD entry for KIF7
1. General information
| Official gene symbol | KIF7 |
|---|---|
| Entrez ID | 374654 |
| Gene full name | kinesin family member 7 |
| Other gene symbols | ACLS HLS2 JBTS12 UNQ340 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003777 | Microtubule motor activity | IDA IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005871 | Kinesin complex | IEA | cellular_component |
| GO:0005874 | Microtubule | IEA | cellular_component |
| GO:0005929 | Cilium | IDA | cellular_component |
| GO:0007018 | Microtubule-based movement | IEA | biological_process |
| GO:0008017 | Microtubule binding | IEA | molecular_function |
| GO:0008152 | Metabolic process | IDA | biological_process |
| GO:0045879 | Negative regulation of smoothened signaling pathway | ISS | biological_process |
| GO:0045880 | Positive regulation of smoothened signaling pathway | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9097953763 | 0.0554711257 | 0.9999902473 | 0.4437290264 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0119537826 |
| GSE13712_SHEAR | Down | -0.1362386798 |
| GSE13712_STATIC | Down | -0.2795885838 |
| GSE19018 | Down | -0.1817284349 |
| GSE19899_A1 | Down | -0.3604139545 |
| GSE19899_A2 | Down | -0.4870208369 |
| PubMed_21979375_A1 | Down | -0.9108743742 |
| PubMed_21979375_A2 | Down | -0.2640660726 |
| GSE35957 | Down | -0.5109947347 |
| GSE36640 | Up | 0.0613086032 |
| GSE54402 | Up | 0.1373248214 |
| GSE9593 | Down | -0.9099681562 |
| GSE43922 | Down | -0.2627261175 |
| GSE24585 | Up | 0.0513331758 |
| GSE37065 | Down | -0.0732487551 |
| GSE28863_A1 | Down | -0.0365969504 |
| GSE28863_A2 | Down | -0.0409582310 |
| GSE28863_A3 | Up | 0.1946808896 |
| GSE28863_A4 | Up | 0.1813166065 |
| GSE48662 | Up | 0.4369270204 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT023103 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-342-5p | MIMAT0004694 | MIRT038214 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
