HCSGD entry for KCNC1

1. General information

Official gene symbolKCNC1
Entrez ID3746
Gene full namepotassium voltage-gated channel, Shaw-related subfamily, member 1
Other gene symbolsKV3.1 KV4 NGK2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005249Voltage-gated potassium channel activityIEA TASmolecular_function
GO:0005251Delayed rectifier potassium channel activityIBAmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0006813Potassium ion transportTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0008076Voltage-gated potassium channel complexIEAcellular_component
GO:0030673AxolemmaIEAcellular_component
GO:0032590Dendrite membraneIEAcellular_component
GO:0032809Neuronal cell body membraneIEAcellular_component
GO:0051260Protein homooligomerizationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.77433507090.79718290720.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1384094362
GSE13712_SHEARUp0.0307637896
GSE13712_STATICDown-0.0479610082
GSE19018Up0.1182638154
GSE19899_A1Up0.0792123204
GSE19899_A2Down-0.0846113845
PubMed_21979375_A1Up0.0848023610
PubMed_21979375_A2Down-0.0323396544
GSE35957Up0.0724733283
GSE36640Up0.0280976964
GSE54402Down-0.0331839753
GSE9593Down-0.0373341445
GSE43922Up0.0574479662
GSE24585Up0.0685406248
GSE37065Down-0.0625973350
GSE28863_A1Down-0.0646043371
GSE28863_A2Down-0.0929072359
GSE28863_A3Up0.4009058554
GSE28863_A4Down-0.0128322668
GSE48662Up0.0023831674

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

DalfampridineDB06637 -

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT016942MicroarrayFunctional MTI (Weak)18185580
hsa-miR-92a-3pMIMAT0000092MIRT049632CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.