HCSGD entry for KCNB1

1. General information

Official gene symbolKCNB1
Entrez ID3745
Gene full namepotassium voltage-gated channel, Shab-related subfamily, member 1
Other gene symbolsDRK1 KV2.1 h-DRK1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005251Delayed rectifier potassium channel activityIBAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0006112Energy reserve metabolic processTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0008076Voltage-gated potassium channel complexIEAcellular_component
GO:0015271Outward rectifier potassium channel activityIEAmolecular_function
GO:0030425DendriteIEAcellular_component
GO:0032590Dendrite membraneIEAcellular_component
GO:0032809Neuronal cell body membraneIEAcellular_component
GO:0044281Small molecule metabolic processTASbiological_process
GO:0045211Postsynaptic membraneIEAcellular_component
GO:0047485Protein N-terminus bindingIEAmolecular_function
GO:0050796Regulation of insulin secretionTASbiological_process
GO:0051260Protein homooligomerizationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.30159990880.94435700390.99969783481.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0000895970
GSE13712_SHEARDown-0.0201489984
GSE13712_STATICUp0.0557710605
GSE19018Up0.1380520960
GSE19899_A1Up0.2421072614
GSE19899_A2Up0.0727661996
PubMed_21979375_A1Up0.0236425110
PubMed_21979375_A2Down-0.1304156165
GSE35957Up0.2179502456
GSE36640Up0.0585657897
GSE54402Up0.0900951762
GSE9593Down-0.0742540738
GSE43922Up0.0231708843
GSE24585Down-0.0237282985
GSE37065Down-0.0022738446
GSE28863_A1Up0.4136147196
GSE28863_A2Up0.1212955531
GSE28863_A3Down-0.1238143066
GSE28863_A4Up0.0913472025
GSE48662Up0.5019895562

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

DalfampridineDB06637 -

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.