HCSGD entry for KCNA6


1. General information

Official gene symbolKCNA6
Entrez ID3742
Gene full namepotassium voltage-gated channel, shaker-related subfamily, member 6
Other gene symbolsHBK2 KV1.6
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005249Voltage-gated potassium channel activityTASmolecular_function
GO:0005251Delayed rectifier potassium channel activityIBAmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0006813Potassium ion transportTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0008076Voltage-gated potassium channel complexIEAcellular_component
GO:0051260Protein homooligomerizationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.51977377760.69707585200.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0393267051
GSE13712_SHEARDown-0.2386424320
GSE13712_STATICUp0.1501970001
GSE19018Down-0.0004184465
GSE19899_A1Down-0.0755400965
GSE19899_A2Up0.2239126022
PubMed_21979375_A1Down-0.1475192579
PubMed_21979375_A2Down-0.0436362429
GSE35957Up0.0172862148
GSE36640Down-0.1099124688
GSE54402Up0.0918559956
GSE9593Down-0.1435330323
GSE43922Up0.0138646840
GSE24585Down-0.0272055193
GSE37065Down-0.0203252504
GSE28863_A1Down-0.1115925911
GSE28863_A2Up0.1373369652
GSE28863_A3Up0.5732017389
GSE28863_A4Up0.2328053224
GSE48662Up0.0249045407

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

DalfampridineDB06637 -

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.