HCSGD entry for TRIM23
1. General information
| Official gene symbol | TRIM23 |
|---|---|
| Entrez ID | 373 |
| Gene full name | tripartite motif containing 23 |
| Other gene symbols | ARD1 ARFD1 RNF46 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000139 | Golgi membrane | IDA | cellular_component |
| GO:0003924 | GTPase activity | IDA | molecular_function |
| GO:0004842 | Ubiquitin-protein ligase activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005525 | GTP binding | IDA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005765 | Lysosomal membrane | IDA | cellular_component |
| GO:0006184 | GTP catabolic process | IDA TAS | biological_process |
| GO:0007264 | Small GTPase mediated signal transduction | IEA | biological_process |
| GO:0008047 | Enzyme activator activity | TAS | molecular_function |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0016032 | Viral process | IEA | biological_process |
| GO:0016567 | Protein ubiquitination | IDA | biological_process |
| GO:0019003 | GDP binding | IDA | molecular_function |
| GO:0042802 | Identical protein binding | IPI | molecular_function |
| GO:0043085 | Positive regulation of catalytic activity | TAS | biological_process |
| GO:0050790 | Regulation of catalytic activity | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0195906690 | 0.8653932107 | 0.3408754131 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3188436006 |
| GSE13712_SHEAR | Up | 0.5316526396 |
| GSE13712_STATIC | Down | -0.1767936061 |
| GSE19018 | Up | 0.1758119988 |
| GSE19899_A1 | Up | 0.5508155121 |
| GSE19899_A2 | Up | 0.1374066804 |
| PubMed_21979375_A1 | Up | 0.7811367784 |
| PubMed_21979375_A2 | Up | 0.2251830210 |
| GSE35957 | Up | 0.1154821826 |
| GSE36640 | Up | 0.9414735203 |
| GSE54402 | Up | 0.1672782667 |
| GSE9593 | Up | 0.2328633671 |
| GSE43922 | Up | 0.2908674542 |
| GSE24585 | Up | 0.5865319525 |
| GSE37065 | Up | 0.0666951847 |
| GSE28863_A1 | Down | -0.0691459523 |
| GSE28863_A2 | Up | 0.2872774728 |
| GSE28863_A3 | Down | -0.8392540323 |
| GSE28863_A4 | Down | -0.1825388870 |
| GSE48662 | Down | -0.1342651910 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-132-3p | MIMAT0000426 | MIRT021830 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024310 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026946 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-33a-5p | MIMAT0000091 | MIRT028184 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-455-5p | MIMAT0003150 | MIRT040741 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
