HCSGD entry for ABCC6
1. General information
| Official gene symbol | ABCC6 |
|---|---|
| Entrez ID | 368 |
| Gene full name | ATP-binding cassette, sub-family C (CFTR/MRP), member 6 |
| Other gene symbols | ABC34 ARA EST349056 GACI2 MLP1 MOAT-E MOATE MRP6 PXE PXE1 URG7 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005215 | Transporter activity | TAS | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0006810 | Transport | TAS | biological_process |
| GO:0007601 | Visual perception | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016323 | Basolateral plasma membrane | IEA | cellular_component |
| GO:0016324 | Apical plasma membrane | IEA | cellular_component |
| GO:0016328 | Lateral plasma membrane | IEA | cellular_component |
| GO:0042493 | Response to drug | TAS | biological_process |
| GO:0042626 | ATPase activity, coupled to transmembrane movement of substances | IEA | molecular_function |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7852707306 | 0.8236882565 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0009669750 |
| GSE13712_SHEAR | Down | -0.1551637687 |
| GSE13712_STATIC | Up | 0.0161358679 |
| GSE19018 | Down | -0.0371342306 |
| GSE19899_A1 | Down | -0.0383188719 |
| GSE19899_A2 | Down | -0.2290284844 |
| PubMed_21979375_A1 | Down | -0.0542577685 |
| PubMed_21979375_A2 | Down | -0.0870417858 |
| GSE35957 | Up | 0.0354753906 |
| GSE36640 | Up | 0.2815984947 |
| GSE54402 | Up | 0.0068727170 |
| GSE9593 | Up | 0.0477835092 |
| GSE43922 | Up | 0.1143127446 |
| GSE24585 | Up | 0.1900722711 |
| GSE37065 | Down | -0.0274904630 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Up | 0.0199255489 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
