HCSGD entry for IPP
1. General information
| Official gene symbol | IPP |
|---|---|
| Entrez ID | 3652 |
| Gene full name | intracisternal A particle-promoted polypeptide |
| Other gene symbols | KLHL27 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003779 | Actin binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0015629 | Actin cytoskeleton | TAS | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2335160404 | 0.1922587212 | 0.9171980609 | 0.8509768430 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0888030944 |
| GSE13712_SHEAR | Up | 0.3571006715 |
| GSE13712_STATIC | Up | 0.4231761181 |
| GSE19018 | Down | -0.0379595080 |
| GSE19899_A1 | Down | -0.1293465652 |
| GSE19899_A2 | Up | 0.2438534787 |
| PubMed_21979375_A1 | Down | -0.0271394603 |
| PubMed_21979375_A2 | Down | -0.0894698921 |
| GSE35957 | Up | 0.2114462460 |
| GSE36640 | Up | 0.5510170348 |
| GSE54402 | Down | -0.3005998745 |
| GSE9593 | Up | 0.4749047504 |
| GSE43922 | Down | -0.1174807416 |
| GSE24585 | Up | 0.4406001145 |
| GSE37065 | Down | -0.0601237882 |
| GSE28863_A1 | Down | -0.2752184544 |
| GSE28863_A2 | Down | -0.3956469778 |
| GSE28863_A3 | Down | -0.8632789518 |
| GSE28863_A4 | Down | -0.2611331917 |
| GSE48662 | Up | 0.4563273786 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-21-5p | MIMAT0000076 | MIRT030826 | Microarray | Functional MTI (Weak) | 18591254 |
| hsa-miR-222-3p | MIMAT0000279 | MIRT046572 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 25346044 | Thus, PINCH-2 participates in decreased systemic recurrence by competitively regulating IPP complex formation with PINCH-1, thereby suppressing autocrine and paracrine effects on motility in colon cancer |
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