HCSGD entry for INSL3

1. General information

Official gene symbolINSL3
Entrez ID3640
Gene full nameinsulin-like 3 (Leydig cell)
Other gene symbolsRLF RLNL ley-I-L
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001556Oocyte maturationIEAbiological_process
GO:0001664G-protein coupled receptor bindingIEAmolecular_function
GO:0001701In utero embryonic developmentIEAbiological_process
GO:0002020Protease bindingIPImolecular_function
GO:0005102Receptor bindingTASmolecular_function
GO:0005158Insulin receptor bindingTASmolecular_function
GO:0005179Hormone activityIEAmolecular_function
GO:0005576Extracellular regionIEA TAScellular_component
GO:0005615Extracellular spaceIEAcellular_component
GO:0007193Adenylate cyclase-inhibiting G-protein coupled receptor signaling pathwayIEAbiological_process
GO:0007267Cell-cell signalingTASbiological_process
GO:0007283SpermatogenesisTASbiological_process
GO:0008284Positive regulation of cell proliferationIEAbiological_process
GO:0008285Negative regulation of cell proliferationIEAbiological_process
GO:0008584Male gonad developmentIEAbiological_process
GO:0030819Positive regulation of cAMP biosynthetic processIEAbiological_process
GO:0043066Negative regulation of apoptotic processIEAbiological_process
GO:0048471Perinuclear region of cytoplasmIEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.42362971770.77768287300.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1507473339
GSE13712_SHEARUp0.0035865322
GSE13712_STATICUp0.0495705242
GSE19018Up0.0582582778
GSE19899_A1Up0.0248738960
GSE19899_A2Down-0.1317088704
PubMed_21979375_A1Up0.1437647103
PubMed_21979375_A2Down-0.1401415300
GSE35957Up0.1654058018
GSE36640Up0.0723129510
GSE54402Up0.0698778844
GSE9593Down-0.0814841896
GSE43922Up0.1497949392
GSE24585Up0.1083864996
GSE37065Up0.0718211142
GSE28863_A1Down-0.3883904692
GSE28863_A2Down-0.0783655076
GSE28863_A3Up0.3206890259
GSE28863_A4Up0.0266334421
GSE48662Up0.1502535457

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.