HCSGD entry for INCENP
1. General information
| Official gene symbol | INCENP |
|---|---|
| Entrez ID | 3619 |
| Gene full name | inner centromere protein antigens 135/155kDa |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000278 | Mitotic cell cycle | TAS | biological_process |
| GO:0000775 | Chromosome, centromeric region | IDA | cellular_component |
| GO:0000776 | Kinetochore | IDA | cellular_component |
| GO:0000777 | Condensed chromosome kinetochore | IEA | cellular_component |
| GO:0000800 | Lateral element | IEA | cellular_component |
| GO:0000801 | Central element | IEA | cellular_component |
| GO:0000910 | Cytokinesis | IMP | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005721 | Centromeric heterochromatin | IDA | cellular_component |
| GO:0005819 | Spindle | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005874 | Microtubule | IEA | cellular_component |
| GO:0007059 | Chromosome segregation | IMP | biological_process |
| GO:0007067 | Mitosis | IEA | biological_process |
| GO:0010369 | Chromocenter | IEA | cellular_component |
| GO:0030496 | Midbody | IEA | cellular_component |
| GO:0043234 | Protein complex | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9228660309 | 0.0418431936 | 0.9999902473 | 0.3848199511 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2084379713 |
| GSE13712_SHEAR | Up | 0.1489662128 |
| GSE13712_STATIC | Down | -0.1693077841 |
| GSE19018 | Down | -0.0085778028 |
| GSE19899_A1 | Down | -0.0432846512 |
| GSE19899_A2 | Down | -1.6667912394 |
| PubMed_21979375_A1 | Up | 0.0707926305 |
| PubMed_21979375_A2 | Down | -1.1681653879 |
| GSE35957 | Down | -0.1967817659 |
| GSE36640 | Down | -2.0165754027 |
| GSE54402 | Down | -0.2039634634 |
| GSE9593 | Down | -0.1189089128 |
| GSE43922 | Up | 0.0217602188 |
| GSE24585 | Down | -0.2007327914 |
| GSE37065 | Down | -0.0961485569 |
| GSE28863_A1 | Up | 0.0587416380 |
| GSE28863_A2 | Up | 0.3645277509 |
| GSE28863_A3 | Up | 0.2872346626 |
| GSE28863_A4 | Up | 0.1873196483 |
| GSE48662 | Down | -0.5611663079 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| N~6~-cyclohexyl-N~2~-(4-morpholin-4-ylphenyl)-9H-purine-2,6-diamine | DB07340 | - |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-142-3p | MIMAT0000434 | MIRT021587 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-181a-5p | MIMAT0000256 | MIRT025087 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-423-3p | MIMAT0001340 | MIRT042486 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
