HCSGD entry for FOXK2
1. General information
| Official gene symbol | FOXK2 |
|---|---|
| Entrez ID | 3607 |
| Gene full name | forkhead box K2 |
| Other gene symbols | ILF ILF-1 ILF1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000287 | Magnesium ion binding | IDA | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA NAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IC IDA IEA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | NAS | biological_process |
| GO:0006357 | Regulation of transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0007389 | Pattern specification process | IBA | biological_process |
| GO:0008301 | DNA binding, bending | IBA | molecular_function |
| GO:0009790 | Embryo development | IBA | biological_process |
| GO:0009888 | Tissue development | IBA | biological_process |
| GO:0043231 | Intracellular membrane-bounded organelle | IDA | cellular_component |
| GO:0043565 | Sequence-specific DNA binding | IDA IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1888424528 | 0.9050564796 | 0.8469738338 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0243230182 |
| GSE13712_SHEAR | Up | 0.3236944786 |
| GSE13712_STATIC | Up | 0.3617561423 |
| GSE19018 | Down | -0.3845979119 |
| GSE19899_A1 | Up | 0.1227192873 |
| GSE19899_A2 | Up | 0.6824877412 |
| PubMed_21979375_A1 | Up | 0.4015504489 |
| PubMed_21979375_A2 | Up | 0.2824523114 |
| GSE35957 | Down | -0.0106928268 |
| GSE36640 | Down | -0.2013479643 |
| GSE54402 | Up | 0.2603547129 |
| GSE9593 | Up | 0.1178554763 |
| GSE43922 | Up | 0.1146660308 |
| GSE24585 | Up | 0.1624254385 |
| GSE37065 | Down | -0.0719184335 |
| GSE28863_A1 | Down | -0.1969741630 |
| GSE28863_A2 | Down | -0.2015468014 |
| GSE28863_A3 | Up | 0.1688315244 |
| GSE28863_A4 | Up | 0.0313786687 |
| GSE48662 | Up | 0.0146071644 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-122-5p | MIMAT0000421 | MIRT023397 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-769-5p | MIMAT0003886 | MIRT039207 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-425-5p | MIMAT0003393 | MIRT039330 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-18a-3p | MIMAT0002891 | MIRT040827 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-183-5p | MIMAT0000261 | MIRT047114 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
