HCSGD entry for IL5RA

1. General information

Official gene symbolIL5RA
Entrez ID3568
Gene full nameinterleukin 5 receptor, alpha
Other gene symbolsCD125 CDw125 HSIL5R3 IL5R
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002437Inflammatory response to antigenic stimulusIEAbiological_process
GO:0004896Cytokine receptor activityIEAmolecular_function
GO:0004914Interleukin-5 receptor activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005615Extracellular spaceTAScellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0007165Signal transductionTASbiological_process
GO:0008283Cell proliferationTASbiological_process
GO:0016020MembraneIEAcellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0019221Cytokine-mediated signaling pathwayTASbiological_process
GO:0032674Regulation of interleukin-5 productionIEAbiological_process
GO:0038043Interleukin-5-mediated signaling pathwayTASbiological_process
GO:0071310Cellular response to organic substanceIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.71188284260.69964205390.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0975644407
GSE13712_SHEARUp0.0067602169
GSE13712_STATICUp0.0594592422
GSE19018Up0.0575680518
GSE19899_A1Up0.1150820874
GSE19899_A2Up0.0670998113
PubMed_21979375_A1Down-0.1353083152
PubMed_21979375_A2Up0.0823059540
GSE35957Up0.1935322027
GSE36640Up0.0257885996
GSE54402Up0.0503267798
GSE9593Up0.0245520591
GSE43922Up0.0132693640
GSE24585Up0.1297336846
GSE37065Down-0.0232479719
GSE28863_A1Down-0.4652959237
GSE28863_A2Down-0.0437646665
GSE28863_A3Up0.0953219844
GSE28863_A4Up0.1163846379
GSE48662Up0.0177560604

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.