HCSGD entry for IL3RA
1. General information
| Official gene symbol | IL3RA |
|---|---|
| Entrez ID | 3563 |
| Gene full name | interleukin 3 receptor, alpha (low affinity) |
| Other gene symbols | CD123 IL3R IL3RAY IL3RX IL3RY hIL-3Ra |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004896 | Cytokine receptor activity | IEA | molecular_function |
| GO:0004912 | Interleukin-3 receptor activity | TAS | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0019221 | Cytokine-mediated signaling pathway | TAS | biological_process |
| GO:0036016 | Cellular response to interleukin-3 | TAS | biological_process |
| GO:0038156 | Interleukin-3-mediated signaling pathway | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5481343034 | 0.3510968276 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0420319833 |
| GSE13712_SHEAR | Down | -0.7684796319 |
| GSE13712_STATIC | Down | -1.7540087696 |
| GSE19018 | Up | 0.3246348654 |
| GSE19899_A1 | Down | -0.0236465288 |
| GSE19899_A2 | Up | 0.0603723726 |
| PubMed_21979375_A1 | Down | -0.0720465909 |
| PubMed_21979375_A2 | Down | -0.0445236403 |
| GSE35957 | Down | -0.0494499426 |
| GSE36640 | Up | 0.1527792398 |
| GSE54402 | Down | -0.0292349241 |
| GSE9593 | Up | 0.2568992118 |
| GSE43922 | Up | 0.0079766372 |
| GSE24585 | Down | -0.0017620946 |
| GSE37065 | Up | 0.2199344748 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Up | 0.0253285552 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Sargramostim | DB00020 | BTD00035 | BIOD00035 |
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
