HCSGD entry for IL2RG

1. General information

Official gene symbolIL2RG
Entrez ID3561
Gene full nameinterleukin 2 receptor, gamma
Other gene symbolsCD132 CIDX IL-2RG IMD4 P64 SCIDX SCIDX1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004896Cytokine receptor activityIEAmolecular_function
GO:0004911Interleukin-2 receptor activityTASmolecular_function
GO:0004913Interleukin-4 receptor activityTASmolecular_function
GO:0004917Interleukin-7 receptor activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006955Immune responseTASbiological_process
GO:0007165Signal transductionNASbiological_process
GO:0009897External side of plasma membraneISScellular_component
GO:0009986Cell surfaceIEAcellular_component
GO:0016020MembraneIEAcellular_component
GO:0016032Viral processIEAbiological_process
GO:0019221Cytokine-mediated signaling pathwayTASbiological_process
GO:0019976Interleukin-2 bindingIEA ISSmolecular_function
GO:0019982Interleukin-7 bindingIEAmolecular_function
GO:0035771Interleukin-4-mediated signaling pathwayTASbiological_process
GO:0038110Interleukin-2-mediated signaling pathwayTASbiological_process
GO:0038111Interleukin-7-mediated signaling pathwayTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.69010471110.87256168080.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1122863060
GSE13712_SHEARUp0.2914767439
GSE13712_STATICUp0.0172621308
GSE19018Up0.1846306672
GSE19899_A1Up0.0046446544
GSE19899_A2Down-0.0025801960
PubMed_21979375_A1Down-0.2101125167
PubMed_21979375_A2Down-0.2195651372
GSE35957Up0.1746828038
GSE36640Up0.0294449464
GSE54402Up0.0865759398
GSE9593Up0.0558508618
GSE43922Up0.0223881931
GSE24585Up0.1799732483
GSE37065Down-0.0351066995
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Up0.0019568071

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Denileukin diftitoxDB00004 BTD00084 | BIOD00084
AldesleukinDB00041 BTD00082 | BIOD00082

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.