HCSGD entry for IHH

1. General information

Official gene symbolIHH
Entrez ID3549
Gene full nameindian hedgehog
Other gene symbolsBDA1 HHG2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001501Skeletal system developmentIMPbiological_process
GO:0001569Patterning of blood vesselsIEAbiological_process
GO:0001649Osteoblast differentiationIEAbiological_process
GO:0001701In utero embryonic developmentIEAbiological_process
GO:0001708Cell fate specificationIEAbiological_process
GO:0001947Heart loopingISSbiological_process
GO:0002053Positive regulation of mesenchymal cell proliferationIEAbiological_process
GO:0003382Epithelial cell morphogenesisIEAbiological_process
GO:0003406Retinal pigment epithelium developmentIEAbiological_process
GO:0005113Patched bindingIPImolecular_function
GO:0005509Calcium ion bindingIDAmolecular_function
GO:0005615Extracellular spaceIEAcellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0006029Proteoglycan metabolic processIEAbiological_process
GO:0006508ProteolysisIEAbiological_process
GO:0007224Smoothened signaling pathwayIDAbiological_process
GO:0007267Cell-cell signalingIEAbiological_process
GO:0008233Peptidase activityIEAmolecular_function
GO:0009880Embryonic pattern specificationIEAbiological_process
GO:0009968Negative regulation of signal transductionIEAbiological_process
GO:0016539Intein-mediated protein splicingIEAbiological_process
GO:0030704Vitelline membrane formationIEAbiological_process
GO:0031012Extracellular matrixIEAcellular_component
GO:0031016Pancreas developmentIEAbiological_process
GO:0032332Positive regulation of chondrocyte differentiationIEAbiological_process
GO:0032355Response to estradiolIEAbiological_process
GO:0032967Positive regulation of collagen biosynthetic processIEAbiological_process
GO:0033085Negative regulation of T cell differentiation in thymusISSbiological_process
GO:0033088Negative regulation of immature T cell proliferation in thymusISSbiological_process
GO:0033089Positive regulation of T cell differentiation in thymusISSbiological_process
GO:0035264Multicellular organism growthIEAbiological_process
GO:0035988Chondrocyte proliferationIEAbiological_process
GO:0040008Regulation of growthIEAbiological_process
GO:0043066Negative regulation of apoptotic processIEAbiological_process
GO:0045453Bone resorptionIEAbiological_process
GO:0045880Positive regulation of smoothened signaling pathwayISSbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0046638Positive regulation of alpha-beta T cell differentiationISSbiological_process
GO:0046639Negative regulation of alpha-beta T cell differentiationISSbiological_process
GO:0048074Negative regulation of eye pigmentationIEAbiological_process
GO:0048469Cell maturationIEAbiological_process
GO:0048557Embryonic digestive tract morphogenesisIEAbiological_process
GO:0048596Embryonic camera-type eye morphogenesisIEAbiological_process
GO:0048666Neuron developmentIEAbiological_process
GO:0048745Smooth muscle tissue developmentIEAbiological_process
GO:0050679Positive regulation of epithelial cell proliferationIEAbiological_process
GO:0051216Cartilage developmentIEAbiological_process
GO:0060135Maternal process involved in female pregnancyIEAbiological_process
GO:0060220Camera-type eye photoreceptor cell fate commitmentIEAbiological_process
GO:0060323Head morphogenesisIEAbiological_process
GO:0061053Somite developmentISSbiological_process
GO:0072498Embryonic skeletal joint developmentIEAbiological_process
GO:0090136Epithelial cell-cell adhesionIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.85054382430.57043666270.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0605331920
GSE13712_SHEARDown-0.1181783564
GSE13712_STATICDown-0.0958841630
GSE19018Down-0.0475677346
GSE19899_A1Down-0.0556372063
GSE19899_A2Down-0.0483262841
PubMed_21979375_A1Down-0.0246746124
PubMed_21979375_A2Down-0.1975957704
GSE35957Down-0.1261331202
GSE36640Up0.0285872318
GSE54402Up0.0950014910
GSE9593Up0.0184593137
GSE43922Up0.1195807209
GSE24585Down-0.2545849776
GSE37065Up0.0016040936
GSE28863_A1Down-0.0358867528
GSE28863_A2Up0.1747501126
GSE28863_A3Up0.4377434331
GSE28863_A4Up0.0447208896
GSE48662Down-0.0492835162

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.