HCSGD entry for IGKC
1. General information
| Official gene symbol | IGKC |
|---|---|
| Entrez ID | 3514 |
| Gene full name | immunoglobulin kappa constant |
| Other gene symbols | HCAK1 IGKCD Km |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003823 | Antigen binding | NAS | molecular_function |
| GO:0005576 | Extracellular region | TAS | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0006955 | Immune response | NAS | biological_process |
| GO:0006956 | Complement activation | TAS | biological_process |
| GO:0006958 | Complement activation, classical pathway | TAS | biological_process |
| GO:0038095 | Fc-epsilon receptor signaling pathway | TAS | biological_process |
| GO:0038096 | Fc-gamma receptor signaling pathway involved in phagocytosis | TAS | biological_process |
| GO:0045087 | Innate immune response | TAS | biological_process |
| GO:0050776 | Regulation of immune response | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7865059800 | 0.8234580297 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0103830890 |
| GSE13712_SHEAR | Up | 0.0846048230 |
| GSE13712_STATIC | Down | -0.0481540569 |
| GSE19018 | Up | 0.0219737646 |
| GSE19899_A1 | Up | 0.0045490372 |
| GSE19899_A2 | Down | -0.0217304190 |
| PubMed_21979375_A1 | Down | -0.0551783568 |
| PubMed_21979375_A2 | Down | -0.0371045850 |
| GSE35957 | Up | 0.1306070472 |
| GSE36640 | Up | 0.0234447635 |
| GSE54402 | Down | -0.0157832676 |
| GSE9593 | Down | -0.1800925894 |
| GSE43922 | Up | 0.1117646443 |
| GSE24585 | Down | -0.0521687419 |
| GSE37065 | Up | 0.0187511762 |
| GSE28863_A1 | Down | -0.0596362959 |
| GSE28863_A2 | Down | -0.1713518938 |
| GSE28863_A3 | Up | 0.2758480586 |
| GSE28863_A4 | Up | 0.1246687092 |
| GSE48662 | Up | 0.0515967967 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
