HCSGD entry for SKA2
1. General information
| Official gene symbol | SKA2 |
|---|---|
| Entrez ID | 348235 |
| Gene full name | spindle and kinetochore associated complex subunit 2 |
| Other gene symbols | FAM33A |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000278 | Mitotic cell cycle | TAS | biological_process |
| GO:0000940 | Condensed chromosome outer kinetochore | IDA IEA | cellular_component |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005876 | Spindle microtubule | IDA IEA | cellular_component |
| GO:0007059 | Chromosome segregation | IEA IMP | biological_process |
| GO:0007067 | Mitosis | IEA IMP | biological_process |
| GO:0008017 | Microtubule binding | IDA IEA | molecular_function |
| GO:0031110 | Regulation of microtubule polymerization or depolymerization | IDA IEA | biological_process |
| GO:0051301 | Cell division | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8552024087 | 0.0006273204 | 0.9999902473 | 0.0466432203 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.4693261962 |
| GSE13712_SHEAR | Up | 0.9962572821 |
| GSE13712_STATIC | Up | 0.3826225736 |
| GSE19018 | Down | -0.0516755824 |
| GSE19899_A1 | Down | -1.5614580244 |
| GSE19899_A2 | Down | -1.0307824865 |
| PubMed_21979375_A1 | Down | -1.3170577228 |
| PubMed_21979375_A2 | Down | -1.5712617835 |
| GSE35957 | Down | -1.0998708891 |
| GSE36640 | Down | -0.8224748248 |
| GSE54402 | Down | -0.4120766266 |
| GSE9593 | Down | -0.8632986008 |
| GSE43922 | Down | -1.3827640212 |
| GSE24585 | Up | 0.6635546538 |
| GSE37065 | Down | -0.5165077848 |
| GSE28863_A1 | Down | -0.8230859400 |
| GSE28863_A2 | Down | -0.1337358286 |
| GSE28863_A3 | Down | -0.9350112109 |
| GSE28863_A4 | Up | 0.4863680613 |
| GSE48662 | Down | -0.4111725104 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-375 | MIMAT0000728 | MIRT019891 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051441 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
