HCSGD entry for IGBP1
1. General information
| Official gene symbol | IGBP1 |
|---|---|
| Entrez ID | 3476 |
| Gene full name | immunoglobulin (CD79A) binding protein 1 |
| Other gene symbols | ALPHA-4 IBP1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | IMP | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | NAS | cellular_component |
| GO:0007165 | Signal transduction | NAS | biological_process |
| GO:0008601 | Protein phosphatase type 2A regulator activity | IDA | molecular_function |
| GO:0031434 | Mitogen-activated protein kinase kinase binding | IEA | molecular_function |
| GO:0032873 | Negative regulation of stress-activated MAPK cascade | IMP | biological_process |
| GO:0034612 | Response to tumor necrosis factor | IMP | biological_process |
| GO:0035306 | Positive regulation of dephosphorylation | IEA | biological_process |
| GO:0035308 | Negative regulation of protein dephosphorylation | IEA | biological_process |
| GO:0042113 | B cell activation | IEA | biological_process |
| GO:0043154 | Negative regulation of cysteine-type endopeptidase activity involved in apoptotic process | IMP | biological_process |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0060632 | Regulation of microtubule-based movement | IMP | biological_process |
| GO:0070555 | Response to interleukin-1 | IMP | biological_process |
| GO:2001234 | Negative regulation of apoptotic signaling pathway | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3641381065 | 0.4326700467 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1129151269 |
| GSE13712_SHEAR | Down | -0.5160192574 |
| GSE13712_STATIC | Down | -0.3747445972 |
| GSE19018 | Up | 0.4357408088 |
| GSE19899_A1 | Up | 0.1135016906 |
| GSE19899_A2 | Down | -0.1694422569 |
| PubMed_21979375_A1 | Up | 0.5825302077 |
| PubMed_21979375_A2 | Down | -0.0518635767 |
| GSE35957 | Down | -0.0290168580 |
| GSE36640 | Up | 0.3231710811 |
| GSE54402 | Up | 0.0790998005 |
| GSE9593 | Up | 0.1484906118 |
| GSE43922 | Down | -0.1818851868 |
| GSE24585 | Up | 0.3554488002 |
| GSE37065 | Down | -0.2087098830 |
| GSE28863_A1 | Down | -0.0091299033 |
| GSE28863_A2 | Down | -0.2505491062 |
| GSE28863_A3 | Down | -0.2812725203 |
| GSE28863_A4 | Up | 0.1335118093 |
| GSE48662 | Up | 0.2176109069 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 24063161 | 1%) was significantly lower than that of group A (4 |
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