HCSGD entry for MACC1


1. General information

Official gene symbolMACC1
Entrez ID346389
Gene full namemetastasis associated in colon cancer 1
Other gene symbols7A5 SH3BP4L
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005634NucleusIEAcellular_component
GO:0005737CytoplasmIEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006355Regulation of transcription, DNA-templatedIEAbiological_process
GO:0008083Growth factor activityIEAmolecular_function
GO:0051781Positive regulation of cell divisionIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.64174710310.94128075300.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0195113072
GSE13712_SHEARUp0.0219723775
GSE13712_STATICUp0.0496444749
GSE19018Up0.1333687579
GSE19899_A1Up0.0732944893
GSE19899_A2Down-0.0401984931
PubMed_21979375_A1Up0.0065932528
PubMed_21979375_A2Up0.0077306291
GSE35957Up0.3414423358
GSE36640Up0.0548990638
GSE54402Down-0.0388836852
GSE9593Up0.0040121102
GSE43922Up0.0979551827
GSE24585Up0.0608856583
GSE37065Up0.0164044385
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Down-0.1312143430

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-143-3pMIMAT0000435MIRT006469Luciferase reporter assay//qRT-PCR//Western blotFunctional MTI22533346
hsa-miR-130b-5pMIMAT0004680MIRT038281CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.