HCSGD entry for IFNGR1
1. General information
| Official gene symbol | IFNGR1 |
|---|---|
| Entrez ID | 3459 |
| Gene full name | interferon gamma receptor 1 |
| Other gene symbols | CD119 IFNGR |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004906 | Interferon-gamma receptor activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005783 | Endoplasmic reticulum | IEA | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0009615 | Response to virus | TAS | biological_process |
| GO:0014069 | Postsynaptic density | IEA | cellular_component |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0019221 | Cytokine-mediated signaling pathway | TAS | biological_process |
| GO:0019955 | Cytokine binding | IEA | molecular_function |
| GO:0030425 | Dendrite | IEA | cellular_component |
| GO:0031982 | Vesicle | IEA | cellular_component |
| GO:0060333 | Interferon-gamma-mediated signaling pathway | TAS | biological_process |
| GO:0060334 | Regulation of interferon-gamma-mediated signaling pathway | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0116419551 | 0.8086856502 | 0.2718557522 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2225186781 |
| GSE13712_SHEAR | Down | -0.0161191806 |
| GSE13712_STATIC | Down | -0.1118513081 |
| GSE19018 | Up | 0.2749729662 |
| GSE19899_A1 | Up | 0.6112305261 |
| GSE19899_A2 | Up | 0.7556902323 |
| PubMed_21979375_A1 | Up | 0.6707412197 |
| PubMed_21979375_A2 | Up | 0.5625876313 |
| GSE35957 | Down | -0.3963453983 |
| GSE36640 | Up | 0.8024292941 |
| GSE54402 | Up | 0.3350502557 |
| GSE9593 | Up | 0.1799453086 |
| GSE43922 | Up | 0.6871161772 |
| GSE24585 | Down | -0.3230316462 |
| GSE37065 | Up | 0.3869873893 |
| GSE28863_A1 | Up | 0.3619838476 |
| GSE28863_A2 | Up | 0.6170668445 |
| GSE28863_A3 | Down | -0.3316957599 |
| GSE28863_A4 | Down | -0.3654876675 |
| GSE48662 | Down | -0.1516732558 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Interferon gamma-1b | DB00033 | BTD00017 | BIOD00017 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT005032 | Flow//Luciferase reporter assay//Northern blot | Functional MTI | 19877012 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027722 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-181b-5p | MIMAT0000257 | MIRT047257 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-196a-5p | MIMAT0000226 | MIRT048216 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
