HCSGD entry for IFNAR2

1. General information

Official gene symbolIFNAR2
Entrez ID3455
Gene full nameinterferon (alpha, beta and omega) receptor 2
Other gene symbolsIFN-R IFN-alpha-REC IFNABR IFNARB
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004905Type I interferon receptor activityIDA IEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005576Extracellular regionTAScellular_component
GO:0005615Extracellular spaceIDA IEAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneIDAcellular_component
GO:0006357Regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0007166Cell surface receptor signaling pathwayTASbiological_process
GO:0007259JAK-STAT cascadeTASbiological_process
GO:0008283Cell proliferationIEAbiological_process
GO:0009615Response to virusTASbiological_process
GO:0019221Cytokine-mediated signaling pathwayTASbiological_process
GO:0019901Protein kinase bindingIPImolecular_function
GO:0019962Type I interferon bindingIPImolecular_function
GO:0035455Response to interferon-alphaIDAbiological_process
GO:0060337Type I interferon signaling pathwayTASbiological_process
GO:0060338Regulation of type I interferon-mediated signaling pathwayTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.49124640400.25582312980.99999024730.9700364448

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1530118397
GSE13712_SHEARDown-0.6205711770
GSE13712_STATICDown-0.4709850304
GSE19018Down-0.0413071586
GSE19899_A1Down-0.1317356518
GSE19899_A2Up0.4804913480
PubMed_21979375_A1Down-0.2865909624
PubMed_21979375_A2Up0.3294836130
GSE35957Down-0.3112561046
GSE36640Up0.0853911910
GSE54402Down-0.1123614371
GSE9593Down-0.1647728335
GSE43922Up0.2444518583
GSE24585Down-0.3918732170
GSE37065Up0.5687343065
GSE28863_A1Up0.2135065933
GSE28863_A2Up0.4054328796
GSE28863_A3Down-0.1754649547
GSE28863_A4Up0.1047353975
GSE48662Up0.0943086607

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Peginterferon alfa-2aDB00008 BTD00043 | BIOD00043
Interferon alfa-n1DB00011 BTD00096 | BIOD00096 | DB00084
Interferon alfa-n3DB00018 BTD00023 | BIOD00023
Peginterferon alfa-2bDB00022 BTD00048 | BIOD00048
Interferon beta-1aDB00060 BTD00093 | BIOD00093
Interferon beta-1bDB00068 BTD00078 | BIOD00078
Interferon alfacon-1DB00069 BTD00062 | BIOD00062
Interferon Alfa-2b, RecombinantDB00105 BTD00066 | BIOD00066
omega interferonDB05472 -

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-106b-5pMIMAT0000680MIRT020448MicroarrayFunctional MTI (Weak)17242205
hsa-miR-484MIMAT0002174MIRT042241CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.