HCSGD entry for IFNA16

1. General information

Official gene symbolIFNA16
Entrez ID3449
Gene full nameinterferon, alpha 16
Other gene symbolsIFN-alphaO
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002250Adaptive immune responseIBAbiological_process
GO:0002286T cell activation involved in immune responseIBAbiological_process
GO:0002323Natural killer cell activation involved in immune responseIBAbiological_process
GO:0005125Cytokine activityIBAmolecular_function
GO:0005132Type I interferon receptor bindingIBAmolecular_function
GO:0005576Extracellular regionTAScellular_component
GO:0005615Extracellular spaceIBAcellular_component
GO:0006959Humoral immune responseIBAbiological_process
GO:0007596Blood coagulationTASbiological_process
GO:0019221Cytokine-mediated signaling pathwayIBA TASbiological_process
GO:0030183B cell differentiationIBAbiological_process
GO:0033141Positive regulation of peptidyl-serine phosphorylation of STAT proteinIBAbiological_process
GO:0042100B cell proliferationIBAbiological_process
GO:0043330Response to exogenous dsRNAIBAbiological_process
GO:0045087Innate immune responseIBA TASbiological_process
GO:0045343Regulation of MHC class I biosynthetic processIBAbiological_process
GO:0051607Defense response to virusIEAbiological_process
GO:0060337Type I interferon signaling pathwayTASbiological_process
GO:0060338Regulation of type I interferon-mediated signaling pathwayTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.85963452760.58800319140.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1647358484
GSE13712_SHEARDown-0.0055583576
GSE13712_STATICUp0.1333159106
GSE19018Down-0.0885842328
GSE19899_A1Up0.2295731205
GSE19899_A2Up0.0147919609
PubMed_21979375_A1Up0.0552191286
PubMed_21979375_A2Down-0.0650196136
GSE35957Up0.0799622942
GSE36640Down-0.0631725033
GSE54402Down-0.0173221882
GSE9593Down-0.0060005246
GSE43922Down-0.0666162818
GSE24585Down-0.1099683362
GSE37065Down-0.0020603997
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Down-0.0060858276

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.