HCSGD entry for IFNA14


1. General information

Official gene symbolIFNA14
Entrez ID3448
Gene full nameinterferon, alpha 14
Other gene symbolsIFN-alphaH LEIF2H
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002250Adaptive immune responseIBAbiological_process
GO:0002286T cell activation involved in immune responseIBAbiological_process
GO:0002323Natural killer cell activation involved in immune responseIBAbiological_process
GO:0005125Cytokine activityIBAmolecular_function
GO:0005126Cytokine receptor bindingTASmolecular_function
GO:0005132Type I interferon receptor bindingIBAmolecular_function
GO:0005576Extracellular regionTAScellular_component
GO:0005615Extracellular spaceIBAcellular_component
GO:0006959Humoral immune responseIBAbiological_process
GO:0007596Blood coagulationTASbiological_process
GO:0019221Cytokine-mediated signaling pathwayIBA TASbiological_process
GO:0030183B cell differentiationIBAbiological_process
GO:0033141Positive regulation of peptidyl-serine phosphorylation of STAT proteinIBAbiological_process
GO:0042100B cell proliferationIBAbiological_process
GO:0043330Response to exogenous dsRNAIBAbiological_process
GO:0045087Innate immune responseIBA TASbiological_process
GO:0045343Regulation of MHC class I biosynthetic processIBAbiological_process
GO:0051607Defense response to virusIEAbiological_process
GO:0060337Type I interferon signaling pathwayTASbiological_process
GO:0060338Regulation of type I interferon-mediated signaling pathwayTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.50063338020.84758374680.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1008101697
GSE13712_SHEARUp0.1111474710
GSE13712_STATICDown-0.0347185573
GSE19018Up0.1414108331
GSE19899_A1Down-0.0257164253
GSE19899_A2Up0.1009523479
PubMed_21979375_A1Down-0.1996714103
PubMed_21979375_A2Down-0.0556107235
GSE35957Up0.1096047882
GSE36640Up0.0916002116
GSE54402Up0.0658637614
GSE9593Down-0.1703354201
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1Up0.2922790321
GSE28863_A2Down-0.1201519587
GSE28863_A3Down-0.0217270951
GSE28863_A4Up0.1612234177
GSE48662Up0.0653248990

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.