HCSGD entry for IFNA2

1. General information

Official gene symbolIFNA2
Entrez ID3440
Gene full nameinterferon, alpha 2
Other gene symbolsIFN-alphaA IFNA IFNA2B INFA2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005125Cytokine activityIEAmolecular_function
GO:0005132Type I interferon receptor bindingTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005576Extracellular regionTAScellular_component
GO:0005615Extracellular spaceIEAcellular_component
GO:0006915Apoptotic processTASbiological_process
GO:0006954Inflammatory responseTASbiological_process
GO:0007166Cell surface receptor signaling pathwayTASbiological_process
GO:0007267Cell-cell signalingTASbiological_process
GO:0007596Blood coagulationTASbiological_process
GO:0010629Negative regulation of gene expressionIDAbiological_process
GO:0019221Cytokine-mediated signaling pathwayTASbiological_process
GO:0042517Positive regulation of tyrosine phosphorylation of Stat3 proteinIDAbiological_process
GO:0045087Innate immune responseTASbiological_process
GO:0045581Negative regulation of T cell differentiationIDAbiological_process
GO:0045892Negative regulation of transcription, DNA-templatedIDAbiological_process
GO:0046597Negative regulation of viral entry into host cellIDAbiological_process
GO:0051607Defense response to virusIDAbiological_process
GO:0060337Type I interferon signaling pathwayTASbiological_process
GO:0060338Regulation of type I interferon-mediated signaling pathwayTASbiological_process
GO:2000552Negative regulation of T-helper 2 cell cytokine productionIDAbiological_process
GO:2000663Negative regulation of interleukin-5 secretionIDAbiological_process
GO:2000666Negative regulation of interleukin-13 secretionIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.71676697690.59194358500.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0599412272
GSE13712_SHEARDown-0.0275736216
GSE13712_STATICUp0.2886788911
GSE19018Up0.0950357562
GSE19899_A1Down-0.1795015994
GSE19899_A2Up0.3439848243
PubMed_21979375_A1Down-0.0300197760
PubMed_21979375_A2Up0.0183381740
GSE35957Down-0.0521645971
GSE36640Down-0.0928598596
GSE54402Down-0.0455454163
GSE9593Up0.0789492940
GSE43922Up0.0938210455
GSE24585Down-0.2636760182
GSE37065Up0.0080249244
GSE28863_A1Up0.1827094884
GSE28863_A2Down-0.0392812167
GSE28863_A3Up0.0353184092
GSE28863_A4Down-0.1376081927
GSE48662Down-0.0435248848

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.