HCSGD entry for IFIT2
1. General information
| Official gene symbol | IFIT2 |
|---|---|
| Entrez ID | 3433 |
| Gene full name | interferon-induced protein with tetratricopeptide repeats 2 |
| Other gene symbols | G10P2 GARG-39 IFI-54 IFI-54K IFI54 IFIT-2 ISG-54 K ISG-54K ISG54 P54 cig42 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005783 | Endoplasmic reticulum | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0008637 | Apoptotic mitochondrial changes | TAS | biological_process |
| GO:0009615 | Response to virus | IDA IMP | biological_process |
| GO:0019221 | Cytokine-mediated signaling pathway | TAS | biological_process |
| GO:0032091 | Negative regulation of protein binding | IDA | biological_process |
| GO:0035457 | Cellular response to interferon-alpha | IEA | biological_process |
| GO:0043065 | Positive regulation of apoptotic process | IDA | biological_process |
| GO:0051607 | Defense response to virus | IEA | biological_process |
| GO:0060337 | Type I interferon signaling pathway | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0007500095 | 0.0206878804 | 0.0773316602 | 0.2780737621 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2068339058 |
| GSE13712_SHEAR | Up | 2.3308359236 |
| GSE13712_STATIC | Up | 1.9855812215 |
| GSE19018 | Up | 0.7446962126 |
| GSE19899_A1 | Down | -0.0266041465 |
| GSE19899_A2 | Down | -0.7339024409 |
| PubMed_21979375_A1 | Down | -1.9375244898 |
| PubMed_21979375_A2 | Down | -1.0772197107 |
| GSE35957 | Down | -1.5804753938 |
| GSE36640 | Up | 1.4984362502 |
| GSE54402 | Down | -1.0151825823 |
| GSE9593 | Up | 1.0852273966 |
| GSE43922 | Down | -1.5939516047 |
| GSE24585 | Up | 2.2288673770 |
| GSE37065 | Up | 1.8661780590 |
| GSE28863_A1 | Up | 0.0184412314 |
| GSE28863_A2 | Up | 2.5697035233 |
| GSE28863_A3 | Down | -1.1956165425 |
| GSE28863_A4 | Up | 0.1433327223 |
| GSE48662 | Up | 0.2885230756 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022752 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-1 | MIMAT0000416 | MIRT023835 | Microarray | Functional MTI (Weak) | 18668037 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
