HCSGD entry for IDI1
1. General information
| Official gene symbol | IDI1 |
|---|---|
| Entrez ID | 3422 |
| Gene full name | isopentenyl-diphosphate delta isomerase 1 |
| Other gene symbols | IPP1 IPPI1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000287 | Magnesium ion binding | IDA | molecular_function |
| GO:0004452 | Isopentenyl-diphosphate delta-isomerase activity | IDA IEA | molecular_function |
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0005777 | Peroxisome | IDA IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006695 | Cholesterol biosynthetic process | TAS | biological_process |
| GO:0008299 | Isoprenoid biosynthetic process | IDA IEA | biological_process |
| GO:0016787 | Hydrolase activity | IEA | molecular_function |
| GO:0030145 | Manganese ion binding | IDA | molecular_function |
| GO:0035634 | Response to stilbenoid | IEA | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0050992 | Dimethylallyl diphosphate biosynthetic process | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0603540481 | 0.5375908970 | 0.5321872362 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.7182509160 |
| GSE13712_SHEAR | Up | 0.1388130490 |
| GSE13712_STATIC | Down | -0.3084588081 |
| GSE19018 | Down | -0.4739437237 |
| GSE19899_A1 | Up | 0.6434142770 |
| GSE19899_A2 | Up | 0.7011979811 |
| PubMed_21979375_A1 | Down | -0.0210188613 |
| PubMed_21979375_A2 | Up | 0.4056347431 |
| GSE35957 | Down | -0.2955295785 |
| GSE36640 | Up | 0.4676977838 |
| GSE54402 | Up | 0.1756365428 |
| GSE9593 | Down | -0.2107509179 |
| GSE43922 | Up | 0.4332217118 |
| GSE24585 | Down | -0.0410853838 |
| GSE37065 | Up | 0.3934725001 |
| GSE28863_A1 | Down | -0.1990872798 |
| GSE28863_A2 | Up | 0.2751076621 |
| GSE28863_A3 | Down | -0.5454919842 |
| GSE28863_A4 | Up | 0.1194140997 |
| GSE48662 | Down | -0.5097786630 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Dimethylallyl Diphosphate | DB01785 | EXPT01221 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016465 | Proteomics | Functional MTI (Weak) | 21512034 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024849 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026527 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029567 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT032320 | Proteomics | Functional MTI (Weak) | 18668040 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
