HCSGD entry for IDH3B
1. General information
| Official gene symbol | IDH3B |
|---|---|
| Entrez ID | 3420 |
| Gene full name | isocitrate dehydrogenase 3 (NAD+) beta |
| Other gene symbols | H-IDHB RP46 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000287 | Magnesium ion binding | IEA | molecular_function |
| GO:0004449 | Isocitrate dehydrogenase (NAD+) activity | IEA | molecular_function |
| GO:0005739 | Mitochondrion | TAS | cellular_component |
| GO:0005759 | Mitochondrial matrix | TAS | cellular_component |
| GO:0006099 | Tricarboxylic acid cycle | TAS | biological_process |
| GO:0006102 | Isocitrate metabolic process | IEA | biological_process |
| GO:0006103 | 2-oxoglutarate metabolic process | IEA | biological_process |
| GO:0006734 | NADH metabolic process | IEA | biological_process |
| GO:0009055 | Electron carrier activity | TAS | molecular_function |
| GO:0044237 | Cellular metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0051287 | NAD binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1025876334 | 0.7265525854 | 0.6667182963 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.7831957383 |
| GSE13712_SHEAR | Down | -0.2188838400 |
| GSE13712_STATIC | Down | -0.1841407569 |
| GSE19018 | Up | 0.0347444019 |
| GSE19899_A1 | Up | 0.2283260371 |
| GSE19899_A2 | Up | 0.7821817307 |
| PubMed_21979375_A1 | Up | 1.2771504854 |
| PubMed_21979375_A2 | Up | 0.8122256754 |
| GSE35957 | Down | -0.3591528563 |
| GSE36640 | Down | -0.4045610230 |
| GSE54402 | Up | 0.2725251496 |
| GSE9593 | Down | -0.3388950287 |
| GSE43922 | Up | 0.2178420073 |
| GSE24585 | Down | -0.0332550190 |
| GSE37065 | Down | -0.0500976156 |
| GSE28863_A1 | Down | -0.0323801169 |
| GSE28863_A2 | Down | -0.2059149730 |
| GSE28863_A3 | Down | -0.3416600545 |
| GSE28863_A4 | Up | 0.1733542168 |
| GSE48662 | Down | -0.0897482296 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| NADH | DB00157 | NUTR00041 | DB01907 | EXPT02287 | DB03527 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-103a-2-5p | MIMAT0009196 | MIRT035766 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040424 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-342-3p | MIMAT0000753 | MIRT043662 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
