HCSGD entry for SPOPL
1. General information
| Official gene symbol | SPOPL |
|---|---|
| Entrez ID | 339745 |
| Gene full name | speckle-type POZ protein-like |
| Other gene symbols | BTBD33 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0016567 | Protein ubiquitination | IEA | biological_process |
| GO:0031397 | Negative regulation of protein ubiquitination | IMP | biological_process |
| GO:0031463 | Cul3-RING ubiquitin ligase complex | IDA | cellular_component |
| GO:0043161 | Proteasome-mediated ubiquitin-dependent protein catabolic process | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2684259527 | 0.3095159075 | 0.9655364307 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3366058731 |
| GSE13712_SHEAR | Up | 0.1474508417 |
| GSE13712_STATIC | Up | 0.0867297658 |
| GSE19018 | Down | -0.3504646408 |
| GSE19899_A1 | Up | 0.3683431744 |
| GSE19899_A2 | Down | -0.2293282172 |
| PubMed_21979375_A1 | Up | 0.7373215349 |
| PubMed_21979375_A2 | Down | -0.0592021165 |
| GSE35957 | Up | 0.3290212847 |
| GSE36640 | Up | 0.0113188847 |
| GSE54402 | Up | 0.3675616687 |
| GSE9593 | Down | -0.5058049919 |
| GSE43922 | Up | 0.3321873136 |
| GSE24585 | Up | 0.1143997083 |
| GSE37065 | Down | -0.0993376625 |
| GSE28863_A1 | Up | 0.0195839410 |
| GSE28863_A2 | Up | 0.4892198986 |
| GSE28863_A3 | Down | -0.3574384533 |
| GSE28863_A4 | Down | -0.2307960365 |
| GSE48662 | Down | -0.3341920226 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-130b-3p | MIMAT0000691 | MIRT020138 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT027973 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-324-5p | MIMAT0000761 | MIRT043207 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
