HCSGD entry for PRSS53
1. General information
| Official gene symbol | PRSS53 |
|---|---|
| Entrez ID | 339105 |
| Gene full name | protease, serine, 53 |
| Other gene symbols | POL3S UNQ308 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004252 | Serine-type endopeptidase activity | IEA | molecular_function |
| GO:0005576 | Extracellular region | IEA | cellular_component |
| GO:0006508 | Proteolysis | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9236394628 | 0.2398329927 | 0.9999902473 | 0.9430673936 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2578877627 |
| GSE13712_SHEAR | Down | -0.1423283115 |
| GSE13712_STATIC | Down | -0.1183957403 |
| GSE19018 | Up | 0.1327600368 |
| GSE19899_A1 | Down | -0.1638159879 |
| GSE19899_A2 | Down | -0.1527983612 |
| PubMed_21979375_A1 | Up | 0.0531519639 |
| PubMed_21979375_A2 | Down | -0.5457834768 |
| GSE35957 | Down | -0.2334501069 |
| GSE36640 | Up | 0.1146570801 |
| GSE54402 | Down | -0.2230406194 |
| GSE9593 | Up | 0.1328631671 |
| GSE43922 | Up | 0.0716585379 |
| GSE24585 | Down | -0.0829115639 |
| GSE37065 | Down | -0.1113867380 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Up | 0.4071589863 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT016806 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
