HCSGD entry for NLRP10

1. General information

Official gene symbolNLRP10
Entrez ID338322
Gene full nameNLR family, pyrin domain containing 10
Other gene symbolsCLR11.1 NALP10 NOD8 PAN5 PYNOD
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002827Positive regulation of T-helper 1 type immune responseIEA ISSbiological_process
GO:0005524ATP bindingIEAmolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0019897Extrinsic component of plasma membraneIDAcellular_component
GO:0035397Helper T cell enhancement of adaptive immune responseIEA ISSbiological_process
GO:0036336Dendritic cell migrationIEA ISSbiological_process
GO:0045087Innate immune responseIEAbiological_process
GO:0050829Defense response to Gram-negative bacteriumIMPbiological_process
GO:0050832Defense response to fungusIEA ISSbiological_process
GO:2000318Positive regulation of T-helper 17 type immune responseIEA ISSbiological_process
GO:2000484Positive regulation of interleukin-8 secretionIMPbiological_process
GO:2000778Positive regulation of interleukin-6 secretionIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.13819686940.39691344550.74862596171.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.3382344149
GSE13712_SHEARDown-0.0566761903
GSE13712_STATICDown-0.0044601460
GSE19018Up0.0700815202
GSE19899_A1Up0.1202662573
GSE19899_A2Up0.2648599148
PubMed_21979375_A1Up1.9787127818
PubMed_21979375_A2Down-0.0026542338
GSE35957Up0.2363271427
GSE36640Up0.1860744363
GSE54402Down-1.8773141660
GSE9593Up0.0473370589
GSE43922Down-0.0962696053
GSE24585Up0.1379340538
GSE37065Down-0.2971074089
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Up0.9969865244

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017739MicroarrayFunctional MTI (Weak)18185580
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.