HCSGD entry for HTR4
1. General information
| Official gene symbol | HTR4 |
|---|---|
| Entrez ID | 3360 |
| Gene full name | 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled |
| Other gene symbols | 5-HT4 5-HT4R |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004993 | Serotonin receptor activity | IDA IEA | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005768 | Endosome | IEA | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | IEA | cellular_component |
| GO:0007186 | G-protein coupled receptor signaling pathway | TAS | biological_process |
| GO:0007187 | G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | TAS | biological_process |
| GO:0007210 | Serotonin receptor signaling pathway | IDA TAS | biological_process |
| GO:0007268 | Synaptic transmission | IEA | biological_process |
| GO:0008284 | Positive regulation of cell proliferation | IMP | biological_process |
| GO:0016020 | Membrane | IDA | cellular_component |
| GO:0032098 | Regulation of appetite | IEA | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6448841875 | 0.7935277839 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0097663733 |
| GSE13712_SHEAR | Down | -0.0005763415 |
| GSE13712_STATIC | Down | -0.0260120616 |
| GSE19018 | Down | -0.0098124105 |
| GSE19899_A1 | Up | 0.0676405269 |
| GSE19899_A2 | Down | -0.0801865983 |
| PubMed_21979375_A1 | Down | -0.0761818951 |
| PubMed_21979375_A2 | Down | -0.0646348494 |
| GSE35957 | Up | 0.1257529841 |
| GSE36640 | Down | -0.0120484614 |
| GSE54402 | Down | -0.0665783104 |
| GSE9593 | Down | -0.0299922297 |
| GSE43922 | Up | 0.0102996068 |
| GSE24585 | Up | 0.1215409731 |
| GSE37065 | Up | 0.0025021438 |
| GSE28863_A1 | Up | 0.2691841501 |
| GSE28863_A2 | Up | 0.0787964141 |
| GSE28863_A3 | Up | 0.2931489887 |
| GSE28863_A4 | Up | 0.1065268586 |
| GSE48662 | Down | -0.0731369594 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Ondansetron | DB00904 | APRD00481 |
| Tegaserod | DB01079 | APRD00096 |
| Piboserod | DB04873 | - |
| Renzapride | DB04917 | - |
| TD-5108 | DB05655 | - |
| TD-2749 | DB05905 | - |
| Prucalopride | DB06480 | - |
| Cinitapride | DB08810 | - |
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
