HCSGD entry for HTR1F
1. General information
| Official gene symbol | HTR1F |
|---|---|
| Entrez ID | 3355 |
| Gene full name | 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled |
| Other gene symbols | 5-HT-1F 5-HT1F 5HT6 HTR1EL MR77 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004993 | Serotonin receptor activity | IDA IMP | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | IMP | cellular_component |
| GO:0007187 | G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | TAS | biological_process |
| GO:0007193 | Adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway | IMP | biological_process |
| GO:0007210 | Serotonin receptor signaling pathway | IDA IMP | biological_process |
| GO:0007268 | Synaptic transmission | TAS | biological_process |
| GO:0051378 | Serotonin binding | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6510663349 | 0.2246127997 | 0.9999902473 | 0.9118785538 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0489738652 |
| GSE13712_SHEAR | Down | -0.0647247264 |
| GSE13712_STATIC | Up | 0.1704052447 |
| GSE19018 | Up | 0.0848619070 |
| GSE19899_A1 | Up | 0.0793451603 |
| GSE19899_A2 | Down | -0.1136673363 |
| PubMed_21979375_A1 | Down | -0.0529795762 |
| PubMed_21979375_A2 | Down | -0.1812603640 |
| GSE35957 | Up | 1.3426345522 |
| GSE36640 | Up | 0.1777538786 |
| GSE54402 | Up | 0.0047049669 |
| GSE9593 | Down | -0.0187943396 |
| GSE43922 | Up | 0.0020598840 |
| GSE24585 | Up | 0.1096327550 |
| GSE37065 | Down | -0.0574247056 |
| GSE28863_A1 | Down | -0.5297368576 |
| GSE28863_A2 | Down | -0.0554338544 |
| GSE28863_A3 | Down | -0.3426886438 |
| GSE28863_A4 | Down | -0.0313749333 |
| GSE48662 | Down | -0.5651174713 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Eletriptan | DB00216 | APRD00945 |
| Zolmitriptan | DB00315 | APRD00376 |
| Ergotamine | DB00696 | APRD00677 |
| Naratriptan | DB00952 | APRD00220 |
| Rizatriptan | DB00953 | APRD00008 |
| Mianserin | DB06148 | - |
| Ketamine | DB01221 | APRD00493 |
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
