HCSGD entry for HSPB2
1. General information
| Official gene symbol | HSPB2 |
|---|---|
| Entrez ID | 3316 |
| Gene full name | heat shock 27kDa protein 2 |
| Other gene symbols | HSP27 Hs.78846 LOH11CR1K MKBP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006986 | Response to unfolded protein | NAS | biological_process |
| GO:0007525 | Somatic muscle development | IEA | biological_process |
| GO:0008047 | Enzyme activator activity | TAS | molecular_function |
| GO:0009408 | Response to heat | IEA | biological_process |
| GO:0043085 | Positive regulation of catalytic activity | TAS | biological_process |
| GO:0050790 | Regulation of catalytic activity | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7887913643 | 0.2789073515 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1273435653 |
| GSE13712_SHEAR | Down | -0.0666779601 |
| GSE13712_STATIC | Down | -0.0621355066 |
| GSE19018 | Up | 0.1395241658 |
| GSE19899_A1 | Down | -0.3434879624 |
| GSE19899_A2 | Up | 0.0760363445 |
| PubMed_21979375_A1 | Down | -0.3438212767 |
| PubMed_21979375_A2 | Down | -0.3860712318 |
| GSE35957 | Up | 0.3642386105 |
| GSE36640 | Up | 0.5258865332 |
| GSE54402 | Down | -0.5290214378 |
| GSE9593 | Up | 0.1496790276 |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.1984690849 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-17-5p | MIMAT0000070 | MIRT031369 | Western blot | Functional MTI | 20209605 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
