HCSGD entry for ACADL

1. General information

Official gene symbolACADL
Entrez ID33
Gene full nameacyl-CoA dehydrogenase, long chain
Other gene symbolsACAD4 LCAD
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000062Fatty-acyl-CoA bindingIEAmolecular_function
GO:0001659Temperature homeostasisISSbiological_process
GO:0003995Acyl-CoA dehydrogenase activityTASmolecular_function
GO:0004466Long-chain-acyl-CoA dehydrogenase activityISSmolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005739MitochondrionIDAcellular_component
GO:0005759Mitochondrial matrixTAScellular_component
GO:0006635Fatty acid beta-oxidationTASbiological_process
GO:0016401Palmitoyl-CoA oxidase activityISSmolecular_function
GO:0019254Carnitine metabolic process, CoA-linkedISSbiological_process
GO:0031966Mitochondrial membraneIEAcellular_component
GO:0033539Fatty acid beta-oxidation using acyl-CoA dehydrogenaseISSbiological_process
GO:0042413Carnitine catabolic processISSbiological_process
GO:0042758Long-chain fatty acid catabolic processIEAbiological_process
GO:0044242Cellular lipid catabolic processISSbiological_process
GO:0044255Cellular lipid metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0045717Negative regulation of fatty acid biosynthetic processISSbiological_process
GO:0046322Negative regulation of fatty acid oxidationISSbiological_process
GO:0050660Flavin adenine dinucleotide bindingIEAmolecular_function
GO:0051289Protein homotetramerizationIEAbiological_process
GO:0055114Oxidation-reduction processISSbiological_process
GO:0090181Regulation of cholesterol metabolic processISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.87927844310.74876434790.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0325352529
GSE13712_SHEARDown-0.1074014001
GSE13712_STATICUp0.0037677892
GSE19018Up0.1061338988
GSE19899_A1Up0.0803862786
GSE19899_A2Down-0.0564609442
PubMed_21979375_A1Up0.1397598329
PubMed_21979375_A2Down-0.0336954448
GSE35957Up0.1709006956
GSE36640Down-0.0139150514
GSE54402Up0.0849905668
GSE9593Down-0.0606671923
GSE43922Up0.0151252454
GSE24585Down-0.0890239724
GSE37065Down-0.0100469384
GSE28863_A1Down-0.0867107048
GSE28863_A2Down-0.0033858500
GSE28863_A3Up0.1137429771
GSE28863_A4Down-0.1093710839
GSE48662Down-0.0810820945

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-124-3pMIMAT0000422MIRT022288MicroarrayFunctional MTI (Weak)18668037
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.