HCSGD entry for HSD17B3
1. General information
| Official gene symbol | HSD17B3 |
|---|---|
| Entrez ID | 3293 |
| Gene full name | hydroxysteroid (17-beta) dehydrogenase 3 |
| Other gene symbols | EDH17B3 SDR12C2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0006702 | Androgen biosynthetic process | TAS | biological_process |
| GO:0008202 | Steroid metabolic process | TAS | biological_process |
| GO:0016491 | Oxidoreductase activity | IEA | molecular_function |
| GO:0030539 | Male genitalia development | TAS | biological_process |
| GO:0043231 | Intracellular membrane-bounded organelle | TAS | cellular_component |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0047045 | Testosterone 17-beta-dehydrogenase (NADP+) activity | IEA | molecular_function |
| GO:0061370 | Testosterone biosynthetic process | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4434101364 | 0.8630341970 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0237513825 |
| GSE13712_SHEAR | Up | 0.0808031437 |
| GSE13712_STATIC | Down | -0.0138760484 |
| GSE19018 | Up | 0.0461731453 |
| GSE19899_A1 | Up | 0.1444826548 |
| GSE19899_A2 | Down | -0.1037040473 |
| PubMed_21979375_A1 | Up | 0.0715032654 |
| PubMed_21979375_A2 | Down | -0.2018903268 |
| GSE35957 | Up | 0.2330580628 |
| GSE36640 | Up | 0.1578619670 |
| GSE54402 | Up | 0.0780569057 |
| GSE9593 | Down | -0.0473343918 |
| GSE43922 | Up | 0.0135658186 |
| GSE24585 | Up | 0.1777254407 |
| GSE37065 | Up | 0.2499221012 |
| GSE28863_A1 | Down | -0.1121559269 |
| GSE28863_A2 | Down | -0.0461435607 |
| GSE28863_A3 | Up | 0.1645703841 |
| GSE28863_A4 | Up | 0.1338228907 |
| GSE48662 | Up | 0.0474800872 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| NADH | DB00157 | NUTR00041 | DB01907 | EXPT02287 | DB03527 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018186 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-181a-5p | MIMAT0000256 | MIRT025169 | Microarray | Functional MTI (Weak) | 17612493 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
