HCSGD entry for HRC


1. General information

Official gene symbolHRC
Entrez ID3270
Gene full namehistidine rich calcium binding protein
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005509Calcium ion bindingTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0006936Muscle contractionTASbiological_process
GO:0010881Regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ionTASbiological_process
GO:0033017Sarcoplasmic reticulum membraneIEAcellular_component
GO:0033018Sarcoplasmic reticulum lumenTAScellular_component
GO:0044325Ion channel bindingIPImolecular_function
GO:0051117ATPase bindingIPImolecular_function
GO:0055074Calcium ion homeostasisIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.46583295090.93719268640.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1145944369
GSE13712_SHEARUp0.0029422351
GSE13712_STATICUp0.0551260884
GSE19018Up0.0433040144
GSE19899_A1Up0.2343210405
GSE19899_A2Down-0.0360261382
PubMed_21979375_A1Down-0.0751439495
PubMed_21979375_A2Down-0.0082084787
GSE35957Up0.0373436503
GSE36640Up0.0591616109
GSE54402Down-0.0300434973
GSE9593Up0.0317859020
GSE43922Up0.0224304874
GSE24585Down-0.0383027577
GSE37065Down-0.0009739586
GSE28863_A1Up0.0559026102
GSE28863_A2Down-0.0111313778
GSE28863_A3Up0.2646224792
GSE28863_A4Up0.2556105891
GSE48662Up0.0439343581

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017575MicroarrayFunctional MTI (Weak)18185580
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.