HCSGD entry for HRH1
1. General information
| Official gene symbol | HRH1 |
|---|---|
| Entrez ID | 3269 |
| Gene full name | histamine receptor H1 |
| Other gene symbols | H1-R hisH1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004930 | G-protein coupled receptor activity | TAS | molecular_function |
| GO:0004969 | Histamine receptor activity | ISS | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IDA TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | ISS | cellular_component |
| GO:0006954 | Inflammatory response | TAS | biological_process |
| GO:0007186 | G-protein coupled receptor signaling pathway | TAS | biological_process |
| GO:0007200 | Phospholipase C-activating G-protein coupled receptor signaling pathway | TAS | biological_process |
| GO:0007613 | Memory | IEA | biological_process |
| GO:0008542 | Visual learning | IEA | biological_process |
| GO:0032962 | Positive regulation of inositol trisphosphate biosynthetic process | ISS | biological_process |
| GO:0043114 | Regulation of vascular permeability | IEA | biological_process |
| GO:0045907 | Positive regulation of vasoconstriction | IEA | biological_process |
| GO:0048016 | Inositol phosphate-mediated signaling | ISS | biological_process |
| GO:0048167 | Regulation of synaptic plasticity | IEA | biological_process |
| GO:0048245 | Eosinophil chemotaxis | IEA | biological_process |
| GO:0071420 | Cellular response to histamine | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5495010182 | 0.0248642073 | 0.9999902473 | 0.3043957209 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0329059890 |
| GSE13712_SHEAR | Up | 0.2525172503 |
| GSE13712_STATIC | Down | -0.1809127040 |
| GSE19018 | Up | 0.0101124456 |
| GSE19899_A1 | Down | -0.3400850636 |
| GSE19899_A2 | Down | -1.6235420284 |
| PubMed_21979375_A1 | Down | -1.2694826092 |
| PubMed_21979375_A2 | Down | -1.2279759020 |
| GSE35957 | Down | -0.1912058431 |
| GSE36640 | Down | -0.3670603581 |
| GSE54402 | Down | -0.7595928715 |
| GSE9593 | Up | 0.4414620364 |
| GSE43922 | Down | -0.9371959597 |
| GSE24585 | Up | 0.1343980551 |
| GSE37065 | Up | 0.0272741542 |
| GSE28863_A1 | Up | 0.6330492634 |
| GSE28863_A2 | Up | 0.6378709736 |
| GSE28863_A3 | Down | -0.2158200344 |
| GSE28863_A4 | Down | -0.0291340873 |
| GSE48662 | Up | 0.0714159029 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-192-5p | MIMAT0000222 | MIRT004851 | Luciferase reporter assay//qRT-PCR//Reporter assay;Microarray;Other | Functional MTI | 19074876 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022836 | Microarray | Functional MTI (Weak) | 18668037 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
