HCSGD entry for HOXC11
1. General information
| Official gene symbol | HOXC11 |
|---|---|
| Entrez ID | 3227 |
| Gene full name | homeobox C11 |
| Other gene symbols | HOX3H |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | IDA | molecular_function |
| GO:0001077 | RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription | IDA | molecular_function |
| GO:0001656 | Metanephros development | IEA | biological_process |
| GO:0001759 | Organ induction | IEA | biological_process |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0006366 | Transcription from RNA polymerase II promoter | IDA | biological_process |
| GO:0007492 | Endoderm development | TAS | biological_process |
| GO:0009952 | Anterior/posterior pattern specification | IEA | biological_process |
| GO:0009954 | Proximal/distal pattern formation | IEA | biological_process |
| GO:0042733 | Embryonic digit morphogenesis | IEA | biological_process |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IDA | biological_process |
| GO:0060272 | Embryonic skeletal joint morphogenesis | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4767736142 | 0.6816377303 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0892897680 |
| GSE13712_SHEAR | Down | -0.0719943845 |
| GSE13712_STATIC | Down | -0.0444991044 |
| GSE19018 | Up | 0.0811969060 |
| GSE19899_A1 | Up | 0.0289954740 |
| GSE19899_A2 | Up | 0.1875138278 |
| PubMed_21979375_A1 | Up | 0.3436721993 |
| PubMed_21979375_A2 | Up | 0.0172050751 |
| GSE35957 | Up | 0.1061847734 |
| GSE36640 | Up | 0.1229563454 |
| GSE54402 | Up | 0.0711735330 |
| GSE9593 | Up | 0.1383006542 |
| GSE43922 | Up | 0.0220887830 |
| GSE24585 | Up | 0.3765757537 |
| GSE37065 | Down | -0.0014693221 |
| GSE28863_A1 | Down | -0.0872416659 |
| GSE28863_A2 | Down | -0.5943490829 |
| GSE28863_A3 | Up | 0.1959188874 |
| GSE28863_A4 | Up | 0.0403355293 |
| GSE48662 | Down | -0.0452847021 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-320b | MIMAT0005792 | MIRT036198 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-744-5p | MIMAT0004945 | MIRT037653 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT042340 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-106a-5p | MIMAT0000103 | MIRT048337 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
