HCSGD entry for HOXB7
1. General information
| Official gene symbol | HOXB7 |
|---|---|
| Entrez ID | 3217 |
| Gene full name | homeobox B7 |
| Other gene symbols | HHO.C1 HOX2 HOX2C Hox-2.3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | NAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA NAS | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | NAS | biological_process |
| GO:0007275 | Multicellular organismal development | NAS | biological_process |
| GO:0009952 | Anterior/posterior pattern specification | IEA | biological_process |
| GO:0030099 | Myeloid cell differentiation | IEA | biological_process |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
| GO:0048704 | Embryonic skeletal system morphogenesis | IEA | biological_process |
| GO:0090190 | Positive regulation of branching involved in ureteric bud morphogenesis | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1002947836 | 0.3898243190 | 0.6609561843 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2610145230 |
| GSE13712_SHEAR | Up | 0.1402311998 |
| GSE13712_STATIC | Up | 0.2284547273 |
| GSE19018 | Down | -0.1739641649 |
| GSE19899_A1 | Down | -0.0023778123 |
| GSE19899_A2 | Up | 0.3654275215 |
| PubMed_21979375_A1 | Down | -0.1568050519 |
| PubMed_21979375_A2 | Up | 0.4562025909 |
| GSE35957 | Down | -1.3162884628 |
| GSE36640 | Up | 0.1929742267 |
| GSE54402 | Down | -0.4620582543 |
| GSE9593 | Down | -0.1154660755 |
| GSE43922 | Up | 0.2832079843 |
| GSE24585 | Up | 1.5211796230 |
| GSE37065 | Down | -0.1174180671 |
| GSE28863_A1 | Down | -0.5002992876 |
| GSE28863_A2 | Up | 0.2698487445 |
| GSE28863_A3 | Up | 0.2378478378 |
| GSE28863_A4 | Up | 0.0587434140 |
| GSE48662 | Down | -0.2405062697 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-196a-5p | MIMAT0000226 | MIRT004244 | Immunofluorescence//Luciferase reporter assay//qRT-PCR//Western blot | Functional MTI | 20480203 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT030282 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-204-5p | MIMAT0000265 | NA | hsa-miR-204 | 20369013 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
