HCSGD entry for HOXA3
1. General information
| Official gene symbol | HOXA3 |
|---|---|
| Entrez ID | 3200 |
| Gene full name | homeobox A3 |
| Other gene symbols | HOX1 HOX1E |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001525 | Angiogenesis | IEP | biological_process |
| GO:0001974 | Blood vessel remodeling | IEA | biological_process |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0008284 | Positive regulation of cell proliferation | IEA | biological_process |
| GO:0009952 | Anterior/posterior pattern specification | IEA | biological_process |
| GO:0010159 | Specification of organ position | IEA | biological_process |
| GO:0021615 | Glossopharyngeal nerve morphogenesis | IEA | biological_process |
| GO:0030878 | Thyroid gland development | IEA | biological_process |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
| GO:0048538 | Thymus development | IEA | biological_process |
| GO:0048645 | Organ formation | IEA | biological_process |
| GO:0048704 | Embryonic skeletal system morphogenesis | IEA | biological_process |
| GO:0051216 | Cartilage development | IEA | biological_process |
| GO:0060017 | Parathyroid gland development | IEA | biological_process |
| GO:0071837 | HMG box domain binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9505491091 | 0.0057814103 | 0.9999902473 | 0.1535544904 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1909833549 |
| GSE13712_SHEAR | Down | -0.2004409997 |
| GSE13712_STATIC | Up | 0.0611227198 |
| GSE19018 | Down | -0.4616368392 |
| GSE19899_A1 | Down | -0.9877418579 |
| GSE19899_A2 | Down | -1.4518959428 |
| PubMed_21979375_A1 | Down | -1.8681185974 |
| PubMed_21979375_A2 | Down | -1.6179785179 |
| GSE35957 | Down | -0.5168605696 |
| GSE36640 | Down | -1.5203859740 |
| GSE54402 | Down | -0.6836136412 |
| GSE9593 | Down | -0.3848914857 |
| GSE43922 | Down | -0.0515636131 |
| GSE24585 | Up | 1.0495626002 |
| GSE37065 | Down | -0.1306321783 |
| GSE28863_A1 | Up | 0.1057280664 |
| GSE28863_A2 | Up | 0.1518746453 |
| GSE28863_A3 | Up | 0.0824750688 |
| GSE28863_A4 | Up | 0.0236881762 |
| GSE48662 | Up | 0.1995113183 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-210-3p | MIMAT0000267 | MIRT003164 | immunoprecipitaion//Microarray//qRT-PCR | Functional MTI (Weak) | 19826008 |
| hsa-miR-151a-5p | MIMAT0004697 | MIRT019529 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022611 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-7-5p | MIMAT0000252 | MIRT025796 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-103a-3p | MIMAT0000101 | MIRT027069 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031721 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-1296-5p | MIMAT0005794 | MIRT036095 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-99b-5p | MIMAT0000689 | MIRT044187 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT047615 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
