HCSGD entry for HOXA1

1. General information

Official gene symbolHOXA1
Entrez ID3198
Gene full namehomeobox A1
Other gene symbolsBSAS HOX1 HOX1F
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0007275Multicellular organismal developmentTASbiological_process
GO:0007605Sensory perception of soundIDAbiological_process
GO:0007634Optokinetic behaviorIDAbiological_process
GO:0008045Motor neuron axon guidanceIEAbiological_process
GO:0009653Anatomical structure morphogenesisIMPbiological_process
GO:0009952Anterior/posterior pattern specificationIEAbiological_process
GO:0021569Rhombomere 3 developmentIEAbiological_process
GO:0021570Rhombomere 4 developmentIEAbiological_process
GO:0021571Rhombomere 5 developmentIEAbiological_process
GO:0021599Abducens nerve formationIMPbiological_process
GO:0021612Facial nerve structural organizationIEAbiological_process
GO:0021754Facial nucleus developmentIEAbiological_process
GO:0021953Central nervous system neuron differentiationIEAbiological_process
GO:0042473Outer ear morphogenesisIDAbiological_process
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0048702Embryonic neurocranium morphogenesisIMPbiological_process
GO:0048839Inner ear developmentIMPbiological_process
GO:0048844Artery morphogenesisIMPbiological_process
GO:0050795Regulation of behaviorIDAbiological_process
GO:0050890CognitionIDAbiological_process
GO:0050905Neuromuscular processIDAbiological_process
GO:0060840Artery developmentIMPbiological_process
GO:0060876Semicircular canal formationIMPbiological_process
GO:0090102Cochlea developmentIMPbiological_process
GO:0090103Cochlea morphogenesisIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.20011623040.24186812430.86287538460.9474938086

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0191307194
GSE13712_SHEARUp0.5316841229
GSE13712_STATICUp0.5956214834
GSE19018Up0.3227752478
GSE19899_A1Up0.0733303915
GSE19899_A2Down-0.9253994405
PubMed_21979375_A1Down-1.1211997592
PubMed_21979375_A2Down-0.3556569933
GSE35957Down-0.2163038265
GSE36640Down-0.3761945525
GSE54402Up0.1944712667
GSE9593Down-0.2819455885
GSE43922Up0.0346079430
GSE24585Up1.0640204766
GSE37065Down-0.1692120019
GSE28863_A1Down-0.1043894234
GSE28863_A2Down-0.0300574745
GSE28863_A3Up0.3080438811
GSE28863_A4Down-0.0458855271
GSE48662Up0.0063267346

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-210-3pMIMAT0000267MIRT000152Luciferase reporter assayFunctional MTI19782034
hsa-miR-10a-5pMIMAT0000253MIRT001140Luciferase reporter assay//qRT-PCR//Western blot//Reporter assay;OtherFunctional MTI16549775
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    • mirRecord

MicroRNA name

mirBase ID

Target site number

MiRNA mature ID

Test method inter

MiRNA regulation site

Reporter target site

Pubmed ID

hsa-miR-10a-5pMIMAT00002531hsa-miR-10a{Western blot}{overexpression by miRNA precursor transfection}16549775
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6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.