HCSGD entry for HNRNPL
1. General information
| Official gene symbol | HNRNPL |
|---|---|
| Entrez ID | 3191 |
| Gene full name | heterogeneous nuclear ribonucleoprotein L |
| Other gene symbols | HNRPL hnRNP-L |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000166 | Nucleotide binding | IEA | molecular_function |
| GO:0000398 | MRNA splicing, via spliceosome | TAS | biological_process |
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA IEA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006396 | RNA processing | TAS | biological_process |
| GO:0006397 | MRNA processing | IEA | biological_process |
| GO:0008380 | RNA splicing | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0019013 | Viral nucleocapsid | IEA | cellular_component |
| GO:0030529 | Ribonucleoprotein complex | IDA IEA | cellular_component |
| GO:0044212 | Transcription regulatory region DNA binding | IDA | molecular_function |
| GO:0045120 | Pronucleus | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8943628586 | 0.0295682041 | 0.9999902473 | 0.3257851171 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2763424227 |
| GSE13712_SHEAR | Up | 0.2423910264 |
| GSE13712_STATIC | Up | 0.0418846023 |
| GSE19018 | Up | 0.0306075309 |
| GSE19899_A1 | Down | -0.3436194190 |
| GSE19899_A2 | Down | -0.3256961615 |
| PubMed_21979375_A1 | Down | -0.9842914600 |
| PubMed_21979375_A2 | Down | -0.2728445900 |
| GSE35957 | Down | -0.5483347652 |
| GSE36640 | Down | -0.7247902157 |
| GSE54402 | Up | 0.0552778293 |
| GSE9593 | Down | -0.4557587676 |
| GSE43922 | Down | -0.1961015476 |
| GSE24585 | Down | -0.0339597071 |
| GSE37065 | Down | -0.1583768296 |
| GSE28863_A1 | Up | 0.1354385525 |
| GSE28863_A2 | Down | -0.1118796419 |
| GSE28863_A3 | Up | 0.3629079267 |
| GSE28863_A4 | Down | -0.0390272481 |
| GSE48662 | Down | -0.0422323022 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016285 | Proteomics | Functional MTI (Weak) | 21512034 |
| hsa-miR-183-5p | MIMAT0000261 | MIRT025002 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT036902 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039633 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-324-5p | MIMAT0000761 | MIRT043110 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-328-3p | MIMAT0000752 | MIRT043796 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-106b-5p | MIMAT0000680 | MIRT044366 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT045182 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-23b-3p | MIMAT0000418 | MIRT046364 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT051122 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT051924 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
