HCSGD entry for HMX1
1. General information
| Official gene symbol | HMX1 |
|---|---|
| Entrez ID | 3166 |
| Gene full name | H6 family homeobox 1 |
| Other gene symbols | H6 NKX5-3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA IMP | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IC | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0007275 | Multicellular organismal development | IEA | biological_process |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
| GO:0045892 | Negative regulation of transcription, DNA-templated | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7774544698 | 0.7575352760 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0248034802 |
| GSE13712_SHEAR | Down | -0.1447993426 |
| GSE13712_STATIC | Down | -0.0480869247 |
| GSE19018 | Up | 0.0090524357 |
| GSE19899_A1 | Down | -0.0908034443 |
| GSE19899_A2 | Up | 0.3764045157 |
| PubMed_21979375_A1 | Up | 0.0101800808 |
| PubMed_21979375_A2 | Down | -0.3031366482 |
| GSE35957 | Down | -0.0258629617 |
| GSE36640 | Up | 0.0919480934 |
| GSE54402 | Up | 0.0066512764 |
| GSE9593 | Down | -0.0119763755 |
| GSE43922 | Up | 0.1027847333 |
| GSE24585 | Down | -0.0749633756 |
| GSE37065 | Down | -0.0473283761 |
| GSE28863_A1 | Up | 0.0010275468 |
| GSE28863_A2 | Up | 0.0086252017 |
| GSE28863_A3 | Up | 0.2781898080 |
| GSE28863_A4 | Down | -0.0096115772 |
| GSE48662 | Up | 0.1514331224 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 24618719 | The Cut homeobox 1 (CUX1) gene is a target of loss-of-heterozygosity in many cancers, yet elevated CUX1 expression is frequently observed and is associated with shorter disease-free survival |
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