HCSGD entry for HMGN2
1. General information
| Official gene symbol | HMGN2 |
|---|---|
| Entrez ID | 3151 |
| Gene full name | high mobility group nucleosomal binding domain 2 |
| Other gene symbols | HMG17 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000785 | Chromatin | IEA | cellular_component |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0031492 | Nucleosomal DNA binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8166203754 | 0.0008117739 | 0.9999902473 | 0.0536851759 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3234516934 |
| GSE13712_SHEAR | Down | -0.1063182754 |
| GSE13712_STATIC | Down | -0.1899963402 |
| GSE19018 | Down | -0.1170123220 |
| GSE19899_A1 | Down | -1.7899317147 |
| GSE19899_A2 | Down | -1.4247154547 |
| PubMed_21979375_A1 | Down | -1.8374809448 |
| PubMed_21979375_A2 | Down | -1.4959749515 |
| GSE35957 | Down | -0.6875971721 |
| GSE36640 | Down | -1.5405923574 |
| GSE54402 | Down | -0.2742421641 |
| GSE9593 | Down | -0.6167731563 |
| GSE43922 | Down | -0.9366695183 |
| GSE24585 | Up | 0.1925035342 |
| GSE37065 | Down | -0.3392465793 |
| GSE28863_A1 | Up | 1.3129139253 |
| GSE28863_A2 | Up | 0.5287121900 |
| GSE28863_A3 | Down | -0.1226030536 |
| GSE28863_A4 | Down | -0.2829130843 |
| GSE48662 | Down | -0.4789434518 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-23a-3p | MIMAT0000078 | MIRT007264 | Luciferase reporter assay | Functional MTI | 23437179 |
| hsa-miR-455-3p | MIMAT0004784 | MIRT037872 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30b-5p | MIMAT0000420 | MIRT046143 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30c-5p | MIMAT0000244 | MIRT047960 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7a-5p | MIMAT0000062 | MIRT052523 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
