HCSGD entry for HMGN1
1. General information
| Official gene symbol | HMGN1 |
|---|---|
| Entrez ID | 3150 |
| Gene full name | high mobility group nucleosome binding domain 1 |
| Other gene symbols | HMG14 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000720 | Pyrimidine dimer repair by nucleotide-excision repair | IEA | biological_process |
| GO:0000785 | Chromatin | IEA | cellular_component |
| GO:0003677 | DNA binding | TAS | molecular_function |
| GO:0005634 | Nucleus | IDA IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006283 | Transcription-coupled nucleotide-excision repair | IEA | biological_process |
| GO:0006325 | Chromatin organization | IEA | biological_process |
| GO:0006357 | Regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0010224 | Response to UV-B | IEA | biological_process |
| GO:0010225 | Response to UV-C | IEA | biological_process |
| GO:0031492 | Nucleosomal DNA binding | IEA | molecular_function |
| GO:0032786 | Positive regulation of DNA-templated transcription, elongation | TAS | biological_process |
| GO:0040034 | Regulation of development, heterochronic | IEA | biological_process |
| GO:0048597 | Post-embryonic camera-type eye morphogenesis | IEA | biological_process |
| GO:0050678 | Regulation of epithelial cell proliferation | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9972880210 | 0.0107439991 | 0.9999902473 | 0.2053219884 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1002822460 |
| GSE13712_SHEAR | Down | -0.1697508999 |
| GSE13712_STATIC | Down | -0.0193556550 |
| GSE19018 | Up | 0.0752631492 |
| GSE19899_A1 | Down | -0.9156351962 |
| GSE19899_A2 | Down | -0.8067546945 |
| PubMed_21979375_A1 | Down | -1.0862474149 |
| PubMed_21979375_A2 | Down | -0.8893829724 |
| GSE35957 | Down | -0.2757295995 |
| GSE36640 | Down | -0.4204112890 |
| GSE54402 | Down | -0.1149861661 |
| GSE9593 | Down | -0.3678636867 |
| GSE43922 | Down | -0.6765011071 |
| GSE24585 | Up | 0.0854965476 |
| GSE37065 | Down | -0.0980135285 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.4554471254 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-197-3p | MIMAT0000227 | MIRT004185 | Microarray | Functional MTI (Weak) | 16822819 |
| hsa-miR-484 | MIMAT0002174 | MIRT041871 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-125b-5p | MIMAT0000423 | MIRT045927 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-100-5p | MIMAT0000098 | MIRT048518 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT051195 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
