HCSGD entry for SOCS7
1. General information
| Official gene symbol | SOCS7 |
|---|---|
| Entrez ID | 30837 |
| Gene full name | suppressor of cytokine signaling 7 |
| Other gene symbols | NAP4 NCKAP4 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0008150 | Biological_process | ND | biological_process |
| GO:0008286 | Insulin receptor signaling pathway | IEA | biological_process |
| GO:0009968 | Negative regulation of signal transduction | IEA | biological_process |
| GO:0016567 | Protein ubiquitination | IEA | biological_process |
| GO:0017124 | SH3 domain binding | NAS | molecular_function |
| GO:0035556 | Intracellular signal transduction | IEA | biological_process |
| GO:0040008 | Regulation of growth | IEA | biological_process |
| GO:0045444 | Fat cell differentiation | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0558775806 | 0.8850955169 | 0.5145136872 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1566882248 |
| GSE13712_SHEAR | Down | -0.2563490135 |
| GSE13712_STATIC | Up | 0.0372215158 |
| GSE19018 | Down | -0.1230005395 |
| GSE19899_A1 | Up | 0.3001530539 |
| GSE19899_A2 | Up | 0.5494164433 |
| PubMed_21979375_A1 | Down | -0.0512873129 |
| PubMed_21979375_A2 | Up | 0.6345695820 |
| GSE35957 | Down | -0.2577959895 |
| GSE36640 | Up | 0.0010780942 |
| GSE54402 | Up | 0.3513416498 |
| GSE9593 | Up | 0.2312983182 |
| GSE43922 | Up | 0.1077451574 |
| GSE24585 | Down | -0.2224796285 |
| GSE37065 | Down | -0.0874289373 |
| GSE28863_A1 | Up | 0.8673250653 |
| GSE28863_A2 | Up | 0.9116279038 |
| GSE28863_A3 | Down | -0.0322524298 |
| GSE28863_A4 | Down | -0.2365008378 |
| GSE48662 | Up | 0.1672048207 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-145-5p | MIMAT0000437 | MIRT007248 | Luciferase reporter assay | Functional MTI | 23392170 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040011 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
