HCSGD entry for CD209
1. General information
| Official gene symbol | CD209 |
|---|---|
| Entrez ID | 30835 |
| Gene full name | CD209 molecule |
| Other gene symbols | CDSIGN CLEC4L DC-SIGN DC-SIGN1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005537 | Mannose binding | TAS | molecular_function |
| GO:0005576 | Extracellular region | IEA | cellular_component |
| GO:0005737 | Cytoplasm | NAS | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0006897 | Endocytosis | IEA | biological_process |
| GO:0007157 | Heterophilic cell-cell adhesion | TAS | biological_process |
| GO:0007159 | Leukocyte cell-cell adhesion | NAS | biological_process |
| GO:0009988 | Cell-cell recognition | TAS | biological_process |
| GO:0016020 | Membrane | TAS | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0019048 | Modulation by virus of host morphology or physiology | TAS | biological_process |
| GO:0019062 | Virion attachment to host cell | TAS | biological_process |
| GO:0019079 | Viral genome replication | NAS | biological_process |
| GO:0019882 | Antigen processing and presentation | NAS | biological_process |
| GO:0030246 | Carbohydrate binding | IEA NAS | molecular_function |
| GO:0035556 | Intracellular signal transduction | NAS | biological_process |
| GO:0042129 | Regulation of T cell proliferation | IDA | biological_process |
| GO:0042605 | Peptide antigen binding | NAS | molecular_function |
| GO:0045087 | Innate immune response | IEA | biological_process |
| GO:0046790 | Virion binding | TAS | molecular_function |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0046968 | Peptide antigen transport | NAS | biological_process |
| GO:0075733 | Intracellular transport of virus | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5320274116 | 0.9415898864 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0443647097 |
| GSE13712_SHEAR | Down | -0.0786205735 |
| GSE13712_STATIC | Up | 0.1159188924 |
| GSE19018 | Up | 0.0501913470 |
| GSE19899_A1 | Up | 0.0603536145 |
| GSE19899_A2 | Up | 0.1556918977 |
| PubMed_21979375_A1 | Up | 0.1489980510 |
| PubMed_21979375_A2 | Down | -0.0694610812 |
| GSE35957 | Up | 0.2208247635 |
| GSE36640 | Up | 0.0176257460 |
| GSE54402 | Up | 0.2256115437 |
| GSE9593 | Down | -0.0750838636 |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | Up | 0.0319210583 |
| GSE28863_A2 | Up | 0.0732868460 |
| GSE28863_A3 | Up | 0.2378907293 |
| GSE28863_A4 | Down | -0.0120960479 |
| GSE48662 | Up | 0.0064073005 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 2 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 23252865 | We also observed that the expressions of IRAK1 and TRAF6, the targets of miR-146a, and DC-SIGN, a target of miR-155 were diminished while miR-146a and miR-155 were augmented during aging |
| 21191073 | CD14(+)CD16(+) monocytes exhibited features of activated cells that included expression of CD209, release of cytokines in response to low-intensity stimulus, and increased capacity to sustain lymphocyte proliferation |
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