HCSGD entry for HGFAC
1. General information
| Official gene symbol | HGFAC |
|---|---|
| Entrez ID | 3083 |
| Gene full name | HGF activator |
| Other gene symbols | HGFA |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004252 | Serine-type endopeptidase activity | IEA | molecular_function |
| GO:0005576 | Extracellular region | NAS | cellular_component |
| GO:0005615 | Extracellular space | IEA | cellular_component |
| GO:0005791 | Rough endoplasmic reticulum | IEA | cellular_component |
| GO:0006508 | Proteolysis | IEA | biological_process |
| GO:0008236 | Serine-type peptidase activity | TAS | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5065595722 | 0.6879155465 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0789770290 |
| GSE13712_SHEAR | Down | -0.4275360691 |
| GSE13712_STATIC | Up | 0.0380913343 |
| GSE19018 | Up | 0.0889957813 |
| GSE19899_A1 | Down | -0.0299138453 |
| GSE19899_A2 | Up | 0.0977626566 |
| PubMed_21979375_A1 | Down | -0.3805179137 |
| PubMed_21979375_A2 | Down | -0.0584457505 |
| GSE35957 | Up | 0.1599154629 |
| GSE36640 | Up | 0.0309488508 |
| GSE54402 | Up | 0.1307574213 |
| GSE9593 | Up | 0.0516597408 |
| GSE43922 | Up | 0.0468276365 |
| GSE24585 | Up | 0.0812836075 |
| GSE37065 | Down | -0.1727952539 |
| GSE28863_A1 | Down | -0.1711646582 |
| GSE28863_A2 | Up | 0.0217284671 |
| GSE28863_A3 | Up | 0.3873764888 |
| GSE28863_A4 | Up | 0.1107886402 |
| GSE48662 | Up | 0.3065760361 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT019046 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
